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Clinical applications of stem cell-derived exosomes
F Tan, X Li, Z Wang, J Li, K Shahzad… - Signal transduction and …, 2024 - nature.com
Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …
certain diseases more successfully than conventional surgery, it nevertheless comes with …
Spinal cord injury: pathophysiology, multimolecular interactions, and underlying recovery mechanisms
Spinal cord injury (SCI) is a destructive neurological and pathological state that causes
major motor, sensory and autonomic dysfunctions. Its pathophysiology comprises acute and …
major motor, sensory and autonomic dysfunctions. Its pathophysiology comprises acute and …
Traumatic spinal cord injury—repair and regeneration
BACKGROUND: Traumatic spinal cord injuries (SCI) have devastating consequences for the
physical, financial, and psychosocial well-being of patients and their caregivers. Expediently …
physical, financial, and psychosocial well-being of patients and their caregivers. Expediently …
Review of advances in electrospinning-based strategies for spinal cord regeneration
Spinal cord injury (SCI) is a devastating neurological condition, commonly leading to
physical and mental deficiencies, pain, other complications, and even death. Most recently …
physical and mental deficiencies, pain, other complications, and even death. Most recently …
Traumatic spinal cord injury
Traumatic spinal cord injury (SCI) has devastating consequences for the physical, social and
vocational well-being of patients. The demographic of SCIs is shifting such that an …
vocational well-being of patients. The demographic of SCIs is shifting such that an …
Neurological recovery following traumatic spinal cord injury: a systematic review and meta-analysis
OBJECTIVE Predicting neurological recovery following traumatic spinal cord injury (TSCI) is
a complex task considering the heterogeneous nature of injury and the inconsistency of …
a complex task considering the heterogeneous nature of injury and the inconsistency of …
Mitochondria as an important target of metformin: The mechanism of action, toxic and side effects, and new therapeutic applications
J Feng, X Wang, X Ye, I Ares, B Lopez-Torres… - Pharmacological …, 2022 - Elsevier
Metformin is the oldest and most commonly used first-line antidiabetic drug because of its
good clinical efficacy, high safety, low cost and easy access. At the same time, in recent …
good clinical efficacy, high safety, low cost and easy access. At the same time, in recent …
Magnesium‐encapsulated injectable hydrogel and 3D‐engineered polycaprolactone conduit facilitate peripheral nerve regeneration
Peripheral nerve injury is a challenging orthopedic condition that can be treated by autograft
transplantation, a gold standard treatment in the current clinical setting. Nevertheless, limited …
transplantation, a gold standard treatment in the current clinical setting. Nevertheless, limited …
Assessment and management of acute spinal cord injury: From point of injury to rehabilitation
LD Hachem, CS Ahuja, MG Fehlings - The journal of spinal cord …, 2017 - Taylor & Francis
Context: Spinal cord injury (SCI) is a devastating condition that can lead to significant
neurological impairment and reduced quality of life. Despite advancements in our …
neurological impairment and reduced quality of life. Despite advancements in our …
3D printed stem‐cell derived neural progenitors generate spinal cord scaffolds
A bioengineered spinal cord is fabricated via extrusion‐based multimaterial 3D bioprinting,
in which clusters of induced pluripotent stem cell (iPSC)‐derived spinal neuronal progenitor …
in which clusters of induced pluripotent stem cell (iPSC)‐derived spinal neuronal progenitor …