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[HTML][HTML] Pleasure systems in the brain
Pleasure is mediated by well-developed mesocorticolimbic circuitry and serves adaptive
functions. In affective disorders, anhedonia (lack of pleasure) or dysphoria (negative affect) …
functions. In affective disorders, anhedonia (lack of pleasure) or dysphoria (negative affect) …
The incentive-sensitization theory of addiction 30 years on
The incentive-sensitization theory (IST) of addiction was first published in 1993, proposing
that (a) brain mesolimbic dopamine systems mediate incentive motivation (“wanting”) for …
that (a) brain mesolimbic dopamine systems mediate incentive motivation (“wanting”) for …
Liking, wanting, and the incentive-sensitization theory of addiction.
Rewards are both “liked” and “wanted,” and those 2 words seem almost interchangeable.
However, the brain circuitry that mediates the psychological process of “wanting” a particular …
However, the brain circuitry that mediates the psychological process of “wanting” a particular …
Evolving concepts of emotion and motivation
This review takes a historical perspective on concepts in the psychology of motivation and
emotion, and surveys recent developments, debates and applications. Old debates over …
emotion, and surveys recent developments, debates and applications. Old debates over …
Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease
Involuntary movements, or dyskinesia, represent a debilitating complication of levodopa (L-
dopa) therapy for Parkinson's disease (PD). L-dopa-induced dyskinesia (LID) are ultimately …
dopa) therapy for Parkinson's disease (PD). L-dopa-induced dyskinesia (LID) are ultimately …
Impulse control disorders and levodopa-induced dyskinesias in Parkinson's disease: an update
Dopaminergic medications used in the treatment of patients with Parkinson's disease are
associated with motor and non-motor behavioural side-effects, such as dyskinesias and …
associated with motor and non-motor behavioural side-effects, such as dyskinesias and …
From prediction error to incentive salience: mesolimbic computation of reward motivation
Reward contains separable psychological components of learning, incentive motivation and
pleasure. Most computational models have focused only on the learning component of …
pleasure. Most computational models have focused only on the learning component of …
New developments in human neurocognition: clinical, genetic, and brain imaging correlates of impulsivity and compulsivity
Impulsivity and compulsivity represent useful conceptualizations that involve dissociable
cognitive functions, which are mediated by neuroanatomically and neurochemically distinct …
cognitive functions, which are mediated by neuroanatomically and neurochemically distinct …
Dissecting components of reward:'liking','wanting', and learning
In recent years significant progress has been made delineating the psychological
components of reward and their underlying neural mechanisms. Here we briefly highlight …
components of reward and their underlying neural mechanisms. Here we briefly highlight …
The debate over dopamine's role in reward: the case for incentive salience
Introduction Debate continues over the precise causal contribution made by mesolimbic
dopamine systems to reward. There are three competing explanatory categories:'liking' …
dopamine systems to reward. There are three competing explanatory categories:'liking' …