Although glutamate is one of the most important excitatory neurotransmitters of the central
nervous system, its excessive extracellular concentration leads to uncontrolled continuous …

L-glutamate (L-Glu) is a nonessential amino acid, but an extensively utilised excitatory
neurotransmitter with critical roles in normal brain function. Aberrant accumulation of L-Glu …

Tau is known for its pathological role in neurodegenerative diseases, including Alzheimer's
disease (AD) and other tauopathies. Tau is found in many subcellular compartments such as …

Objectives. Aluminium, a neurotoxic agent in humans, has been implicated in the
pathogenesis of neurodegenerative disorders. In this study, we examined the behavioral …

Doxorubicin (DOX) is the most widely used broad-spectrum anticancer agent, either alone or
in combination, for most cancers including breast cancer. Long-term use of …

The most recent evidence supports the existence of a link between type 2 diabetes (T2DM)
and Alzheimer's Disease (AD), described by the new term: type 3 diabetes (T3D). The …

Glutamate receptors play a crucial role in the central nervous system and are implicated in
different brain disorders. They play a significant role in the pathogenesis of …

Behavioural inflexibility is a symptom of neuropsychiatric and neurodegenerative disorders
such as Obsessive-Compulsive Disorder, Autism Spectrum Disorder and Alzheimer's …

Glutamate excitotoxicity is implicated in the pathogenesis of numerous diseases, such as
stroke, traumatic brain injury, and Alzheimer's disease, for which insulin resistance is a …

Close connections between depression and type 2 diabetes (T2DM) have been suggested
by many epidemiological and experimental studies. Disturbances in insulin sensitivity due to …