Neutrophil extracellular traps in homeostasis and disease

H Wang, SJ Kim, Y Lei, S Wang, H Wang… - … and Targeted Therapy, 2024‏ - nature.com
Neutrophil extracellular traps (NETs), crucial in immune defense mechanisms, are
renowned for their propensity to expel decondensed chromatin embedded with inflammatory …

Placenta: an old organ with new functions

S Khorami-Sarvestani, N Vanaki, S Shojaeian… - Frontiers in …, 2024‏ - frontiersin.org
The transition from oviparity to viviparity and the establishment of feto-maternal
communications introduced the placenta as the major anatomical site to provide nutrients …

[HTML][HTML] A narrative review on the pathophysiology of preeclampsia

J Torres-Torres, S Espino-y-Sosa… - International Journal of …, 2024‏ - mdpi.com
Preeclampsia (PE) is a multifactorial pregnancy disorder characterized by hypertension and
proteinuria, posing significant risks to both maternal and fetal health. Despite extensive …

Orthogonal design of experiments for engineering of lipid nanoparticles for mRNA delivery to the placenta

HC Safford, KL Swingle, HC Geisler, AG Hamilton… - Small, 2024‏ - Wiley Online Library
During healthy pregnancy, the placenta develops to allow for exchange of nutrients and
oxygen between the mother and the fetus. However, placental dysregulation can lead to …

MicroRNA-510-3p regulated vascular dysfunction in Preeclampsia by targeting Vascular Endothelial Growth Factor A (VEGFA) and its signaling axis

SC Selvakumar, D Sekar - Placenta, 2024‏ - Elsevier
Introduction Preeclampsia (PE) is a pregnancy complication associated with multi-organ
damage and vascular dysfunction. Meanwhile, microRNAs or miRNAs are crucial regulators …

[HTML][HTML] New ideas for the prevention and treatment of preeclampsia and their molecular inspirations

A Sakowicz, M Bralewska… - International Journal of …, 2023‏ - mdpi.com
Preeclampsia (PE) is a pregnancy-specific disorder affecting 4–10% of all expectant women.
It greatly increases the risk of maternal and foetal death. Although the main symptoms …

Deep hybrid model for maternal health risk classification in pregnancy: synergy of ANN and random forest

TO Togunwa, AO Babatunde… - Frontiers in Artificial …, 2023‏ - frontiersin.org
Introduction Maternal health is a critical aspect of public health that affects the wellbeing of
both mothers and infants. Despite medical advancements, maternal mortality rates remain …

Hypertensive disorders in pregnancy: global burden from 1990 to 2019, current research hotspots and emerging trends

R Fu, Y Li, X Li, W Jiang - Current Problems in Cardiology, 2023‏ - Elsevier
Hypertensive disorders in pregnancy (HDP) constitute a worldwide health problem for
pregnant women and their infants. This study provided HDP burden over 1990 to 2019 by …

Machine learning algorithms versus classical regression models in pre-eclampsia prediction: a systematic review

SA Tiruneh, TTT Vu, DL Rolnik, HJ Teede… - Current Hypertension …, 2024‏ - Springer
Abstract Purpose of Review Machine learning (ML) approaches are an emerging alternative
for healthcare risk prediction. We aimed to synthesise the literature on ML and classical …

Potential biomarkers for late-onset and term preeclampsia: A sco** review

L Han, OJ Holland, F Da Silva Costa… - Frontiers in …, 2023‏ - frontiersin.org
Preeclampsia is a progressive, multisystem pregnancy disorder. According to the time of
onset or delivery, preeclampsia has been subclassified into early-onset (< 34 weeks) and …