Posttranslational modification with small ubiquitin-related modifier (SUMO) proteins is now
established as one of the key regulatory protein modifications in eukaryotic cells. Hundreds …

Small ubiquitin-like modifiers (SUMOs) are essential for the regulation of several cellular
processes and are potential therapeutic targets owing to their involvement in diseases such …

SUMOylation is a reversible post-translational modification essential for genome stability.
Using high-resolution MS, we have studied global SUMOylation in human cells in a site …

Ubiquitination regulates many essential cellular processes in eukaryotes. This post-
translational modification (PTM) is typically achieved by E1, E2, and E3 enzymes that …

Sumoylation is an essential post‐translational modification intimately involved in a diverse
range of eukaryotic cellular mechanisms. Small ubiquitin‐like modifier (SUMO) protein …

Covalent posttranslational modification with SUMO (small ubiquitin-related modifier)
modulates functions of a wide range of proteins in eukaryotic cells. Sumoylation affects the …

Motivation: Post-translational modification by the Small Ubiquitin-like Modifier (SUMO)
proteins, a process termed SUMOylation, is involved in many fundamental cellular …

The ubiquitin family member Sumo has important functions in many cellular processes
including DNA repair, transcription and cell division. Numerous studies have shown that …

Reversible modification of proteins by SUMO (small ubiquitin-like modifier) affects a large
number of cellular processes. In striking contrast to the related ubiquitin pathway, only a few …

Sumoylation is an essential post-translational modification that has evolved to regulate
intricate networks within emerging complexities of eukaryotic cells. Thousands of target …