Serotoninergic neurons in the central nervous system im**e on many other neurons and
modulate their neurotransmitter release. This review focuses on 1) the function of …

Adenosine triphosphate (ATP) is released in many synapses in the CNS either together with
other neurotransmitters, such as glutamate and GABA, or on its own. Postsynaptic action of …

Cenobamate is a novel antiepileptic drug under investigation for use in patients with focal
(partial-onset) seizures. To understand its potential molecular mechanism of action, the …

New, more effective pharmacologic treatments for epilepsy are needed, as a substantial
portion of patients (> 30%) are refractory to currently available anti-epileptic drugs …

Chemical transmission between neurons and glial cells is an important element of
integration in the CNS. Here, we describe currents activated by NMDA in cortical astrocytes …

The hippocampus mediates several higher brain functions, such as learning, memory, and
spatial coding. The input region of the hippocampus, the dentate gyrus, plays a critical role …

Early in postnatal development, inhibitory inputs to rat lateral superior olive (LSO) neurons
change from releasing predominantly GABA to releasing predominantly glycine into the …

Brain‐type fatty acid‐binding protein (B‐FABP) belongs to a family of intracellular lipid‐
binding proteins. B‐FABP exhibits a binding affinity to long‐chain fatty acids (FAs) whose …

Hypothalamic inflammation plays an important role in disrupting feeding behavior and
energy homeostasis as well as in the pathogenesis of obesity and diabetes. Here, we show …

One reported mechanism for morphine activation of dopamine (DA) neurons of the ventral
tegmental area (VTA) is the disinhibition model of VTA-DA neurons. Morphine inhibits GABA …