Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives

S Regmi, S Pathak, JO Kim, CS Yong… - European journal of cell …, 2019 - Elsevier
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …

Same or not the same? Comparison of adipose tissue-derived versus bone marrow-derived mesenchymal stem and stromal cells

M Strioga, S Viswanathan, A Darinskas… - Stem cells and …, 2012 - liebertpub.com
Mesenchymal stem/stromal cells (MSCs) comprise a heterogeneous population of cells with
multilineage differentiation potential, the ability to modulate oxidative stress, and secrete …

Microbiome—the missing link in the gut-brain axis: focus on its role in gastrointestinal and mental health

K Skonieczna-Żydecka, W Marlicz, A Misera… - Journal of clinical …, 2018 - mdpi.com
The central nervous system (CNS) and the human gastrointestinal (GI) tract communicate
through the gut-brain axis (GBA). Such communication is bi-directional and involves …

Endogenous, very small embryonic-like stem cells: critical review, therapeutic potential and a look ahead

D Bhartiya, A Shaikh, S Anand, H Patel… - Human …, 2017 - academic.oup.com
BACKGROUND Both pluripotent very small embryonic-like stem cells (VSELs) and induced
pluripotent stem (iPS) cells were reported in 2006. In 2012, a Nobel Prize was awarded for …

A novel view of the adult stem cell compartment from the perspective of a quiescent population of very small embryonic-like stem cells

MZ Ratajczak, J Ratajczak, M Suszynska… - Circulation …, 2017 - Am Heart Assoc
Evidence has accumulated that adult hematopoietic tissues and other organs contain a
population of dormant stem cells (SCs) that are more primitive than other, already restricted …

Characterization of serum cytokine profile in predominantly colonic inflammatory bowel disease to delineate ulcerative and Crohn's colitides

OY Korolkova, JN Myers, ST Pellom… - Clinical Medicine …, 2015 - journals.sagepub.com
Background As accessible diagnostic approaches fail to differentiate between ulcerative
colitis (UC) and Crohn's colitis (CC) in one-third of patients with predominantly colonic …

[PDF][PDF] New advances in stem cell research: practical implications for regenerative medicine

MZ Ratajczak, T Jadczyk, D Pedziwiatr… - Pol Arch Med …, 2014 - ppm.pum.edu.pl
Regenerative medicine is searching for stem cells that can be safely and efficiently
employed for regenera‑tion of damaged solid organs (eg, the heart, brain, or liver). Ideal for …

Mouse bone marrow VSELs exhibit differentiation into three embryonic germ lineages and germ & hematopoietic cells in culture

A Shaikh, S Anand, S Kapoor, R Ganguly… - Stem Cell Reviews and …, 2017 - Springer
Very small embryonic-like stem cells (VSELs) have been reported in various adult tissues,
express pluripotent and primordial germ cells (PGCs) specific markers, are mobilized under …

Molecular and cellular mechanisms involved in mesenchymal stem cell-based therapy of inflammatory bowel diseases

BS Markovic, T Kanjevac, CR Harrell, M Gazdic… - Stem Cell Reviews and …, 2018 - Springer
Mesenchymal stem cells (MSCs) are promising resource for the therapy of inflammatory
bowel diseases (IBDs) on the grounds of their differentiation capabilities and immuno …

Very small embryonic-like stem cells (VSELs) represent a real challenge in stem cell biology: recent pros and cons in the midst of a lively debate

MZ Ratajczak, E Zuba-Surma, W Wojakowski… - Leukemia, 2014 - nature.com
The concept that adult tissue, including bone marrow (BM), contains early-development cells
with broader differentiation potential has again been recently challenged. In response, we …