Small-cell lung cancer (SCLC) represents about 15% of all lung cancers and is marked by
an exceptionally high proliferative rate, strong predilection for early metastasis and poor …

The neurotransmitter acetylcholine (ACh) acts as an autocrine growth factor for human lung
cancer. Several lines of evidence show that lung cancer cells express all of the proteins …

PURPOSE Germline genetic testing (GGT) is now recommended for all patients diagnosed
with ovarian or pancreatic cancer and for a large proportion of patients based solely on a …

Chronic nicotine exposure gives rise to neural adaptations that change whole cell
physiology and behaviour mainly by interacting with neuronal nicotinic acetylcholine …

Background and Purpose Tobacco smoke contains many classes of carcinogens and
although nicotine is unable to initiate tumourigenesis in humans and rodents, it promotes …

Lung cancer (LC) is the most common global cancer. An individual's risk of develo** LC is
mediated by an array of factors, including family history of the disease. Considerable …

Lung scar carcinoma (SC) was first described by Friedrich in 1939 as a type of lung cancer
that originates around peripheral scars in the lung. Scarring in the lung can result from a …

The occurrence and progression of diseases are strongly associated with a combination of
genetic, lifestyle, and environmental factors. Understanding the interplay between genetic …

Screaming headlines in the public press recently an-nounced that research had solved the
age-old riddle of which came first,“the chicken or the egg”—it was the chicken! 1 This classic …

We know that cigarette smoking is a leading preventable cause of carcinogenesis in lung
cancer. Cigarette smoke is a mixture of more than 5000 chemical compounds, among which …