The CB 2 receptor is the peripheral receptor for cannabinoids. It is mainly expressed in
immune tissues, highlighting the possibility that the endocannabinoid system has an …

This review summarizes the importance and recent discoveries of the use of adamantane
derivatives in Medicinal Chemistry. We have organized the article in 4 sections: 1) …

Despite low levels of cannabinoid receptor type 2 (CB2R) expression in the central nervous
system in human and rodents, a growing body of evidence shows CB2R involvement in …

Purpose: Cannabinoids have been recently proposed as a new family of potential antitumor
agents. The present study was undertaken to investigate the expression of the two …

Fluoroquinolones are synthetic antibacterial agents that stabilize the ternary complex of
prokaryotic topoisomerase II enzymes (gyrase and Topo IV), leading to extensive DNA …

It has been well appreciated that the endocannabinoid system can regulate immune
responses via the cannabinoid receptor 2 (CB2), which is primarily expressed by cells of the …

The 1, 8‐naphthyridine group of compounds have gained special attention of researchers
on account of their demonstrating a variety of interesting biological activities. A wide range of …

The cannabinoid receptor subtype 2 (CB2R) represents an interesting and new therapeutic
target for its involvement in the first steps of neurodegeneration as well as in cancer onset …

Cannabinoid type 2 receptor (CB2R), belonging to the endocannabinoid system, is
overexpressed in pathologies characterized by inflammation, and its activation counteracts …

Quinolones are among the most common frameworks present in the bioactive molecules
and hence represent an attractive starting point for the design of combinatorial libraries …