Cell-cell junctions are essential for maintaining tissue integrity and regulating a wide range
of physiological processes. While the disruption of intercellular junctions may lead to …

Thyroid hormones (THs) regulate metabolism in a homeostatic state in an adult organism.
During the prenatal period, prior to the establishment of homeostatic mechanisms, THs …

Recently, surface engineering of the cell membrane with biomaterials has attracted great
attention for various biomedical applications. In this study, we investigated the possibility of …

Lumens are crucial features of the tissue architecture in both the healthy exocrine pancreas,
where ducts shuttle enzymes from the acini to the intestine, and in the precancerous lesions …

Despite the widespread popularity of the" scratch assay," where a pipette is dragged
manually through cultured tissue to create a gap to study cell migration and healing, it …

Receptor tyrosine kinases (RTKs) are thought to play key roles in coordinating cell
movement at single-cell and tissue scales. The recent development of optogenetic tools for …

Despite the widespread popularity of the 'scratch assay', where a pipette is dragged through
cultured tissue to create an injury gap to study cell migration and healing, the manual nature …

Cell migration is a fundamental behavior involved in multicellular development, tissue
regeneration and homeostasis, which is deregulated in cancer. Epithelial cells migrate …

Pancreatic Ductal Adenocarcinoma (PDAC), a form of pancreatic cancer, is highly lethal. To
study morphogenesis and understand disease progression, organoids-in vitro 3D cell …

We have developed a sterile functionalisation method for DAAM-particles based on the work
of Vorselen et al., enabling their integration into epithelial monolayers to measure bead …