Major depressive disorder is one of the most disabling mental disorders worldwide.
Increasing preclinical and clinical studies have highlighted that compositional and functional …

The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …

Depression is the most common mental disorder and a leading cause of disability
worldwide. Despite abundant research, the precise mechanisms underlying the …

Colonic drug delivery can facilitate access to unique therapeutic targets and has the
potential to enhance drug bioavailability whilst reducing off-target effects. Delivering drugs to …

The gut microbiome lies at the intersection between the environment and the host, with the
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …

The gut microbiota contributes to diverse aspects of host physiology, ranging from
immunomodulation to drug metabolism. Changes in the gut microbiota composition are …

The efficacy of drugs widely varies in individuals, and the gut microbiota plays an important
role in this variability. The commensal microbiota living in the human gut encodes several …

Cardiometabolic diseases have become a leading cause of morbidity and mortality globally.
They have been tightly linked to microbiome taxonomic and functional composition, with diet …

Microbiome research is now demonstrating a growing number of bacterial strains and genes
that affect our health. Although CRISPR-derived tools have shown great success in editing …

Despite milestones in preventive measures and treatment, cardiovascular disease (CVD)
remains associated with a high burden of morbidity and mortality. The protracted nature of …