Correlation of blood-based immune molecules with cardiac gene expression profiles reveals insights into Chagas cardiomyopathy pathogenesis

TG Souza-Silva, EGA Neves, C Koh… - Frontiers in …, 2024‏ - frontiersin.org
Introduction Understanding compartmentalized immune responses in target organs is
crucial for elucidating the pathogenesis of various diseases. However, obtaining samples …

TNF-expressing CD1d+ monocytes are associated with the activation of CD4- CD8- T cells in patients with Chagas cardiomyopathy

CC Koh, T Velikkakam, EGA Neves… - Revista da Sociedade …, 2024‏ - SciELO Brasil
Background: Chagas disease cardiomyopathy is characterized by intense immune
activation, with double-negative (DN) T cells as key producers of inflammatory cytokines …

Mendelian Randomization Reveals Causal Pathways Between Plasma Protein Quantitative Trait Loci and Graves' Disease Mediated by Immune Cells

S Cui, Q Liu - medRxiv, 2025‏ - medrxiv.org
Graves' disease (GD) is a prevalent autoimmune disorder characterized by hyperthyroidism
and thyroid dysfunction, driven by thyroid receptor antibodies (TRAb) that activate the thyroid …