Nanoparticles as drug delivery systems: a review of the implication of nanoparticles' physicochemical properties on responses in biological systems

A Yusuf, ARZ Almotairy, H Henidi, OY Alshehri… - Polymers, 2023 - mdpi.com
In the last four decades, nanotechnology has gained momentum with no sign of slowing
down. The application of inventions or products from nanotechnology has revolutionised all …

Therapeutic and diagnostic applications of nanoparticles in the management of COVID-19: a comprehensive overview

O Gholizadeh, S Yasamineh, P Amini, H Afkhami… - Virology Journal, 2022 - Springer
Abstract In December 2019, Coronavirus Disease 2019 (COVID-19) was reported in Wuhan,
China. Comprehensive strategies for quick identification, prevention, control, and remedy of …

Mixed plasticizers aggravated apoptosis by NOD2-RIP2-NF-κB pathway in grass carp hepatocytes

Y Cui, K Yin, Y Zheng, B Wang, Y Qu, S Li… - Journal of hazardous …, 2021 - Elsevier
The wide application of plastics led to the wide exposure of plasticizers to the environment.
As a new environmental pollutant, plasticizers' toxicity researches were far from enough in …

Gelatinase-sensitive nanoparticles loaded with photosensitizer and STAT3 inhibitor for cancer photothermal therapy and immunotherapy

LL Bu, HQ Wang, Y Pan, L Chen, H Wu, X Wu… - Journal of …, 2021 - Springer
Abstract Matrix metalloproteinase (MMP) 2 and 9 are the family members of proteases
normally up-regulated in tumor to enhance the invasion and metastatic of tumor cells, and …

[Retracted] Antioxidant and Anti‐Inflammatory Activities of Coenzyme‐Q10 and Piperine against Cyclophosphamide‐Induced Cytotoxicity in HuH‐7 Cells

NS Al-Johani, M Al-Zharani, NH Aljarba… - BioMed Research …, 2022 - Wiley Online Library
Cyclophosphamide (CP) alkylates DNA and RNA produce crosslinks that cause gene
expression and protein synthesis inhibition to exert its anticancer effect. However, adverse …

Liposomal encapsulation of silver nanoparticles (AgNP) improved nanoparticle uptake and induced redox imbalance to activate caspase-dependent apoptosis

A Yusuf, A Casey - Apoptosis, 2020 - Springer
Macrophages play a crucial role in several diseases' development and progression, such as
in cancer and arthritis through ROS generation and inflammation. This makes macrophages …

[HTML][HTML] Antioxidant and anti-inflammatory activities of lycopene against 5-fluorouracil-induced cytotoxicity in Caco2 cells

NM Alhoshani, M Al-Zharani, B Almutairi… - Saudi Pharmaceutical …, 2022 - Elsevier
fluorouracil (5FU) is widely used to treat colorectal cancer (CC) and its main mechanisms of
anticancer action are through generation of ROS which often result in inflammation. Here …

Investigation of sex-based differences in the immunotoxicity of silver nanoparticles

B Canup, P Rogers, A Paredes, W Manheng… - …, 2024 - Taylor & Francis
The growing application of silver nanoparticles (AgNPs) in consumer, healthcare, and
industrial products has raised concern over potential health implications due to increasing …

[HTML][HTML] Immunotoxicity of stainless-steel nanoparticles obtained after 3D printing

E Olšovská, ML Mikušová, J Tulinská… - Ecotoxicology and …, 2024 - Elsevier
This study aims to investigate the in vitro effects of nanoparticles (NPs) produced during the
selective laser melting (SLM) of 316 L stainless steel metal powder on the immune response …

[HTML][HTML] Nebulized Hybrid Nanoarchaeosomes: Anti-Inflammatory Activity, Anti-Microbial Activity and Cytotoxicity on A549 Cells

SGG Stabile, N Perez, HE Jerez, YR Simioni… - International Journal of …, 2025 - mdpi.com
The properties of two hybrid nanoarchaeosomes (hybrid nanoARCs) made of archaeolipids
extracted from the halophilic archaea Halorubrum tebenquichense and combining the …