Develo** strategies toward safe and effective drug delivery into the central nervous
system (CNS) with improved targeting abilities and reduced off-target effects is crucial. CNS …

The severity and long-term consequences of brain damage in traumatic brain injured (TBI)
patients urgently calls for better neuroprotective/neuroreparative strategies for this …

The restoration of nerve dysfunction after traumatic brain injury (TBI) faces huge challenges
due to the limited self-regenerative abilities of nerve tissues. In situ inductive recovery can …

Exosomes, membrane‐enclosed vesicles, are secreted by all types of cells. Exosomes can
transport various molecules, including proteins, lipids, functional mRNAs, and microRNAs …

Traumatic brain injury is a serious and complex neurological condition that affects millions of
people worldwide. Despite significant advancements in the field of medicine, effective …

Pediatric traumatic brain injury is a cause of major mortality, and resultant neurological
sequelae areassociated with long-term morbidity. Increasing studies have revealed stem …

Introduction: Endothelial glycocalyx damage occurs in numerous pathological conditions
and results in endotheliopathy. Extracellular vesicles, including exosomes and …

Exosomes are the smallest subset of extracellular signaling vesicles secreted by most cells
with the ability to communicate with other tissues and cell types over long distances. Their …

Extracellular vesicles (EVs) are secreted by almost all cell types and contain DNA, RNA,
proteins, lipids and other metabolites. EVs were initially believed to be cellular waste but …

Background Methamphetamine (METH) is a psychostimulant substance with highly
addictive and neurotoxic effects, but no ideal treatment option exists to improve METH …