The c-Jun N-terminal kinase (JNK) is a stress-activated member of MAP kinase family. JNK
activation has been strongly implicated in inflammatory responses, neurodegeneration, and …

Pain is a multidimensional perception and is modified at distinct regions of the neuroaxis.
During enhanced pain, neuroplastic changes occur in the spinal and supraspinal …

Background and Purpose—White matter injury caused by cerebral hypoperfusion may
contribute to the pathophysiology of vascular dementia and stroke, but the underlying …

A1 polarization of astrocytes mediated prolonged inflammation contributing to brain injury in
ischemic stroke. We have previously shown that AD16 protects against neonatal hypoxic …

Aims Oxidative stress is frequently implicated in the pathology of neurodegenerative
diseases. This study aimed to investigate the effects and their underlying mechanism (s) of …

Background Parkinson's disease (PD) is a neurological disorder characterized by the
degeneration of nigrostriatal dopaminergic systems. Free radicals induced by oxidative …

The concept of the neurovascular unit suggests that to be successful, stroke therapies must
protect all neuronal, glial and endothelial components in brain. In this study, we tested the …

3-methyl-1-phenyl-2-pyrazolin-5-one (edaravone), an effective free radical scavenger,
provides neuroprotection in stroke models and patients. In this study, we investigated its …

Aim: Ferulic acid (4-hydroxy-3-methoxycinnamic acid, FA) provides neuroprotection against
apoptosis in a transient middle cerebral artery occlusion (MCAo) model. This study was to …

Nano‐radiosensitization is an emerging concept for cancer therapy and the underlying
rationale embroils enhancement of radiosensitization by nanomaterials. Here we describe a …