Chemico-biological aspects of (−)-epigallocatechin-3-gallate (EGCG) to improve its stability, bioavailability and membrane permeability: Current status and future …

R Sahadevan, S Singh, A Binoy… - Critical Reviews in Food …, 2023 - Taylor & Francis
Natural products have been a bedrock for drug discovery for decades.(−)-Epigallocatechin-3-
gallate (EGCG) is one of the widely studied natural polyphenolic compounds derived from …

Safety assessment of green tea based beverages and dried green tea extracts as nutritional supplements

W Dekant, K Fujii, E Shibata, O Morita… - Toxicology letters, 2017 - Elsevier
The safety of green tea infusions and green tea extract (GTE)-based products is reviewed
regarding catechins. Epigallocatechin 3-gallate (EGCG), the major catechin present in green …

Scientific opinion on the safety of green tea catechins

EFSA Panel on Food Additives and Nutrient … - EFSA …, 2018 - Wiley Online Library
Abstract The EFSA ANS Panel was asked to provide a scientific opinion on the safety of
green tea catechins from dietary sources including preparations such as food supplements …

Stability of (−)-epigallocatechin gallate and its activity in liquid formulations and delivery systems

O Krupkova, SJ Ferguson, K Wuertz-Kozak - The Journal of nutritional …, 2016 - Elsevier
Epigallocatechin gallate (EGCG) has become a popular disease-preventive supplement
worldwide because it may aid in slowing down the onset of age-related diseases such as …

Effects of antioxidant polyphenols on TNF-alpha-related diseases

K Kawaguchi, T Matsumoto… - Current topics in …, 2011 - ingentaconnect.com
Oxidative stress and inflammatory responses sustained for a long period of time cause many
diseases. A proinflammatory cytokine, tumor necrosis factor α (TNF-α), plays a pivotal role in …

Nutritional applications and beneficial health applications of green tea and l‐theanine in some animal species: A review

M Alagawany, ME Abd El‐Hack… - Journal of animal …, 2020 - Wiley Online Library
Green tea (Camellia sinensis) is a popular herbal plant with abundant health benefits, and
thus, it has been used as a potent antioxidant for a long time. Based on the available …

Pharmacokinetics and blood–brain barrier penetration of (+)-catechin and (−)-epicatechin in rats by microdialysis sampling coupled to high-performance liquid …

L Wu, QL Zhang, XY Zhang, C Lv, J Li… - Journal of agricultural …, 2012 - ACS Publications
(+)-Catechin (C) and (−)-epicatechin (EC), as the basic monomer units of flavanols, can be
widely found in natural products or medicinal herbs. Recent pharmacological studies have …

Multistage carcinogenesis process as molecular targets in cancer chemoprevention by epicatechin-3-gallate

MH Pan, YS Chiou, YJ Wang, CT Ho, JK Lin - Food & function, 2011 - pubs.rsc.org
The consumption of green tea has long been associated with a reduced risk of cancer
development.(−)-Epicatechin-3-gallate (ECG) or (−)-epigallocatechin-3-gallate (EGCG) are …

Fyn is a novel target of (−)‐epigallocatechin gallate in the inhibition of JB6 Cl41 cell transformation

Z He, F Tang, S Ermakova, M Li, Q Zhao… - … in cooperation with …, 2008 - Wiley Online Library
The cancer preventive action of (−)‐epigallocatechin gallate (EGCG), found in green tea, is
strongly supported by epidemiology and laboratory research data. However, the mechanism …

Identification of epigallocatechin-3-gallate (EGCG) from green tea using mass spectrometry

I Sivanesan, M Muthu, A Kannan, SSC Pushparaj… - Separations, 2022 - mdpi.com
In an era where humanity is reinstating its lost hope and expectation on natural products,
green tea occupies quite a position for what it has proven to be, in its endeavors for human …