Functions of the neocortex depend on its bidirectional communication with the thalamus, via
cortico-thalamo-cortical (CTC) loops. Recent work dissecting the synaptic connectivity in …

Dendrites have always fascinated researchers: from the artistic drawings by Ramon y Cajal
to the beautiful recordings of today, neuroscientists have been striving to unravel the …

We assembled a semi-automated reconstruction of L2/3 mouse primary visual cortex from∼
250× 140× 90 μm 3 of electron microscopic images, including pyramidal and non-pyramidal …

Circuits in the cerebral cortex consist of thousands of neurons connected by millions of
synapses. A precise understanding of these local networks requires relating circuit activity …

Neuronal networks with strong recurrent connectivity provide the brain with a powerful
means to perform complex computational tasks. However, high-gain excitatory networks are …

The strength of synaptic connections fundamentally determines how neurons influence each
other's firing. Excitatory connection amplitudes between pairs of cortical neurons vary over …

The selectivity of neuronal responses arises from the architecture of excitatory and inhibitory
connections. In the primary visual cortex, the selectivity of a neuron in layer 2/3 for stimulus …

The sensory cortex contains a wide array of neuronal types, which are connected together
into complex but partially stereotyped circuits. Sensory stimuli trigger cascades of electrical …

Predictive coding theories of sensory brain function interpret the hierarchical construction of
the cerebral cortex as a Bayesian, generative model capable of predicting the sensory data …

Recurrent cortical activity sculpts visual perception by refining, amplifying or suppressing
visual input. However, the rules that govern the influence of recurrent activity remain …