An update of epigenetic drugs for the treatment of cancers and brain diseases: a comprehensive review
Epigenetics has long been recognized as a significant field in biology and is defined as the
investigation of any alteration in gene expression patterns that is not attributed to changes in …
investigation of any alteration in gene expression patterns that is not attributed to changes in …
[HTML][HTML] Upstream and downstream regulators of Klotho expression in chronic kidney disease
SS Li, M Sheng, ZY Sun, Y Liang, LX Yu, QF Liu - Metabolism, 2023 - Elsevier
Klotho is a critical protein that protects the kidney. Klotho is severely downregulated in
chronic kidney disease (CKD), and its deficiency is implicated in the pathogenesis and …
chronic kidney disease (CKD), and its deficiency is implicated in the pathogenesis and …
MLCPP 2.0: an updated cell-penetrating peptides and their uptake efficiency predictor
Cell-penetrating peptides (CPPs) translocate into the cell as various biologically active
conjugates and possess numerous biomedical applications. Several machine learning …
conjugates and possess numerous biomedical applications. Several machine learning …
Crossing epigenetic frontiers: the intersection of novel histone modifications and diseases
W Yao, X Hu, X Wang - Signal Transduction and Targeted Therapy, 2024 - nature.com
Histone post-translational modifications (HPTMs), as one of the core mechanisms of
epigenetic regulation, are garnering increasing attention due to their close association with …
epigenetic regulation, are garnering increasing attention due to their close association with …
[HTML][HTML] Epigenetic modifications of hormonal signaling pathways in plant drought response and tolerance for sustainable food security
Drought significantly challenges global food security, necessitating a comprehensive
understanding of plant molecular responses for effective mitigation strategies. Epigenetic …
understanding of plant molecular responses for effective mitigation strategies. Epigenetic …
Epigenetic regulation in lung cancer
Lung cancer is indeed a major cause of cancer‐related deaths worldwide. The development
of tumors involves a complex interplay of genetic, epigenetic, and environmental factors …
of tumors involves a complex interplay of genetic, epigenetic, and environmental factors …
Introduction to epigenetics
Epigenetics is the study of inherited variations in gene expression that do not involve
changes to DNA sequences. Over 200 unique cell types in a human adult have a nearly …
changes to DNA sequences. Over 200 unique cell types in a human adult have a nearly …
Epigenetics and plant hormone dynamics: a functional and methodological perspective
J Rudolf, L Tomovicova, K Panzarova… - Journal of …, 2024 - academic.oup.com
Plant hormones, pivotal regulators of plant growth, development, and response to
environmental cues, have recently emerged as central modulators of epigenetic processes …
environmental cues, have recently emerged as central modulators of epigenetic processes …
Mechanism and therapeutic opportunities of histone modifications in chronic liver disease
Q Cai, C Gan, C Tang, H Wu, J Gao - Frontiers in Pharmacology, 2021 - frontiersin.org
Chronic liver disease (CLD) represents a global health problem, accounting for the heavy
burden of disability and increased health care utilization. Epigenome alterations play an …
burden of disability and increased health care utilization. Epigenome alterations play an …
Protein modification in neurodegenerative diseases
S Ramazi, M Dadzadi, M Darvazi, N Seddigh… - MedComm, 2024 - Wiley Online Library
Posttranslational modifications play a crucial role in governing cellular functions and protein
behavior. Researchers have implicated dysregulated posttranslational modifications in …
behavior. Researchers have implicated dysregulated posttranslational modifications in …