Effects of Intermittent Fasting on Health and Aging Evidence is accumulating that eating in a
6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to …

The interplay between diet, the gut microbiome, and host health is complex. Diets
associated with health have many similarities: high fiber, unsaturated fatty acids, and …

Intermittent fasting (IF) improves cardiometabolic health; however, it is unknown whether
these effects are due solely to weight loss. We conducted the first supervised controlled …

Time-restricted feeding (TRF) regimens have grown in popularity; however, very few studies
have examined their weight-loss efficacy. We conducted the first human trial (Clinicaltrials …

Intermittent fasting diets have become very popular in the past few years, as they can
produce clinically significant weight loss. These diets can be defined, in the simplest of …

Humans in modern societies typically consume food at least three times daily, while
laboratory animals are fed ad libitum. Overconsumption of food with such eating patterns …

Fasting has been practiced for millennia, but, only recently, studies have shed light on its
role in adaptive cellular responses that reduce oxidative damage and inflammation, optimize …

Reduced food intake, avoiding malnutrition, can ameliorate aging and aging-associated
diseases in invertebrate model organisms, rodents, primates, and humans. Recent findings …

Objective Intermittent fasting (IF) is a term used to describe a variety of eating patterns in
which no or few calories are consumed for time periods that can range from 12 hours to …

Chronic caloric restriction (CR) has powerful anticarcinogenic actions in both preclinical and
clinical studies but may be difficult to sustain. As an alternative to CR, there has been …