Type VII secretion systems: structure, functions and transport models
A Rivera-Calzada, N Famelis, O Llorca… - Nature Reviews …, 2021 - nature.com
Type VII secretion systems (T7SSs) have a key role in the secretion of effector proteins in
non-pathogenic mycobacteria and pathogenic mycobacteria such as Mycobacterium …
non-pathogenic mycobacteria and pathogenic mycobacteria such as Mycobacterium …
Not too fat to fight: The emerging role of macrophage fatty acid metabolism in immunity to Mycobacterium tuberculosis
T Laval, L Chaumont, C Demangel - Immunological Reviews, 2021 - Wiley Online Library
While the existence of a special relationship between Mycobacterium tuberculosis (Mtb) and
host lipids has long been known, it remains a challenging enigma. It was clearly established …
host lipids has long been known, it remains a challenging enigma. It was clearly established …
Facile metabolic reprogramming distinguishes mycobacterial adaptation to hypoxia and starvation: ketosis drives starvation-induced persistence in M. bovis BCG
Mycobacteria adapt to infection stresses by entering a reversible non-replicating persistence
(NRP) with slow or no cell growth and broad antimicrobial tolerance. Hypoxia and nutrient …
(NRP) with slow or no cell growth and broad antimicrobial tolerance. Hypoxia and nutrient …
Bacterial type VII secretion: An important player in host‐microbe and microbe‐microbe interactions
Type VII secretion systems (T7SSs) are poorly understood protein export apparatuses found
in mycobacteria and many species of Gram‐positive bacteria. To date, this pathway has …
in mycobacteria and many species of Gram‐positive bacteria. To date, this pathway has …
Host and bacterial lipid metabolism during tuberculosis infections: possibilities to synergise host-and bacteria-directed therapies
T van der Klugt, RHGA van den Biggelaar… - Critical Reviews in …, 2024 - Taylor & Francis
Mycobacterium tuberculosis (Mtb) is the causative pathogen of tuberculosis, the most lethal
infectious disease resulting in 1.3 million deaths annually. Treatments against Mtb are …
infectious disease resulting in 1.3 million deaths annually. Treatments against Mtb are …
Intrabacterial lipid inclusions in mycobacteria: unexpected key players in survival and pathogenesis?
I Mallick, P Santucci, I Poncin, V Point… - FEMS Microbiology …, 2021 - academic.oup.com
Mycobacterial species, including Mycobacterium tuberculosis, rely on lipids to survive and
chronically persist within their hosts. Upon infection, opportunistic and strict pathogenic …
chronically persist within their hosts. Upon infection, opportunistic and strict pathogenic …
PE_PGRS: Vital proteins in promoting mycobacterial survival and modulating host immunity and metabolism
Y **e, Y Zhou, S Liu, XL Zhang - Cellular Microbiology, 2021 - Wiley Online Library
Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tb), is the leading infectious
cause of mortality worldwide. One of the key reasons for M. tb pathogenesis is the capability …
cause of mortality worldwide. One of the key reasons for M. tb pathogenesis is the capability …
Mycobacterium tuberculosis PE31 (Rv3477) Attenuates Host Cell Apoptosis and Promotes Recombinant M. smegmatis Intracellular Survival via Up-regulating …
The Mycobacterium (M.) tuberculosis comprising proline–glutamic acid (PE) subfamily
proteins associate with virulence, pathogenesis, and host-immune modulations. While the …
proteins associate with virulence, pathogenesis, and host-immune modulations. While the …
Structure-function relationship of PE11 esterase of Mycobacterium tuberculosis with respect to its role in virulence
The lipolytic enzymes of Mycobacterium tuberculosis play a critical role in
immunomodulation and virulence. Among these proteins, PE11 which also belongs to the …
immunomodulation and virulence. Among these proteins, PE11 which also belongs to the …
The endogenous galactofuranosidase GlfH1 hydrolyzes mycobacterial arabinogalactan
Despite impressive progress made over the past 20 years in our understanding of
mycolylarabinogalactan-peptidoglycan (mAGP) biogenesis, the mechanisms by which the …
mycolylarabinogalactan-peptidoglycan (mAGP) biogenesis, the mechanisms by which the …