Ca2+ plays a crucial role in excitation-contraction coupling in cardiac myocytes.
Dysfunctional Ca2+ regulation alters the force of contraction and causes cardiac …

Introduction Electrocardiographic (ECG) changes in heart failure with reduced, mildly
reduced, and preserved ejection fractions can be critical in clinical assessment while waiting …

Cardiac arrhythmias and conduction disturbances are accompanied by structural
remodelling of the specialised cardiomyocytes known collectively as the cardiac conduction …

Background: Purkinje fibers (PFs) control timing of ventricular conduction and play a key role
in arrhythmogenesis in heart failure (HF) patients. We investigated the effects of HF on PFs …

The funny current, I f, was first recorded in the heart 40 or more years ago by Dario
DiFrancesco and others. Since then, we have learnt that I f plays an important role in …

Heart failure is associated with atrioventricular (AV) node dysfunction, and AV node
dysfunction in the setting of heart failure is associated with an increased risk of mortality and …

Curcumin, isolated from rhizome of turmeric, has been widely studied as a potential
therapeutic drug for cancer. However, protective effects of curcumin on chronic heart failure …

Aims To determine the prevalence, incidence, predictors, and prognostic implications of PR
interval prolongation in patients referred with suspected heart failure. Methods and results …

Background Severely ill patients with coronavirus disease 2019 (COVID‐19) show an
increased risk of new‐onset atrioventricular blocks (AVBs), associated with high rates of …

Patients with pulmonary arterial hypertension (PAH) have a high burden of arrhythmias,
including arrhythmias arising from sinus node dysfunction, and the aim of this study was to …