Diagnosing antiphospholipid syndrome:'extra-criteria'manifestations and technical advances

S Sciascia, MC Amigo, D Roccatello… - Nature Reviews …, 2017 - nature.com
First described in the early 1980s, antiphospholipid syndrome (APS) is a unique form of
acquired autoimmune thrombophilia in which patients present with clinical features of …

Management of neuropsychiatric systemic lupus erythematosus: current approaches and future perspectives

C Magro-Checa, EJ Zirkzee, TW Huizinga… - Drugs, 2016 - Springer
Neuropsychiatric systemic lupus erythematosus (NPSLE) is a generic definition referring to a
series of neurological and psychiatric symptoms directly related to systemic lupus …

Clinical relevance of HEp-2 indirect immunofluorescent patterns: the International Consensus on ANA patterns (ICAP) perspective

J Damoiseaux, LEC Andrade, OG Carballo… - Annals of the …, 2019 - ard.bmj.com
The indirect immunofluorescence assay (IIFA) on HEp-2 cells is widely used for detection of
antinuclear antibodies (ANA). The dichotomous outcome, negative or positive, is integrated …

C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production and glomerulonephropathy in mice

A Atanasio, V Decman, D White, M Ramos, B Ikiz… - Scientific reports, 2016 - nature.com
The expansion of a hexanucleotide (GGGGCC) repeat in C9ORF72 is the most common
cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Both the …

Neuropsychiatric lupus: a mosaic of clinical presentations

S Kivity, N Agmon-Levin, G Zandman-Goddard… - BMC medicine, 2015 - Springer
Neuropsychiatric symptoms affect nearly half of the patients with systemic lupus
erythematosus; however, the effect on disease severity, quality of life, and prognosis is …

Psychosis: an autoimmune disease?

AAJ Al‐Diwani, TA Pollak, SR Irani, BR Lennox - Immunology, 2017 - Wiley Online Library
Psychotic disorders are common and disabling. Overlaps in clinical course in addition to
epidemiological and genetic associations raise the possibility that autoimmune mechanisms …

Pathogenesis and treatment of neuropsychiatric systemic lupus erythematosus: a review

Y Liu, Z Tu, X Zhang, K Du, Z **e, Z Lin - Frontiers in Cell and …, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease with a
complex pathogenesis. Neuropsychiatric systemic lupus erythematosus (NPSLE) is a …

Anti–ribosomal P protein autoantibodies from patients with neuropsychiatric lupus impair memory in mice

M Bravo‐Zehnder, EM Toledo… - Arthritis & …, 2015 - Wiley Online Library
Objective To define whether anti‐ribosomal P (anti‐P) autoantibodies from patients with
neuropsychiatric systemic lupus erythematosus (NPSLE) impair the function of hippocampal …

Neuropsychiatric systemic lupus erythematosus: molecules involved in its imunopathogenesis, clinical features, and treatment

AA Justiz-Vaillant, D Gopaul, S Soodeen… - Molecules, 2024 - mdpi.com
Systemic lupus erythematosus (SLE) is an idiopathic chronic autoimmune disease that can
affect any organ in the body, including the neurological system. Multiple factors, such as …

Pathogenicity of Lupus Anti–Ribosomal P Antibodies: Role of Cross‐Reacting Neuronal Surface P Antigen in Glutamatergic Transmission and Plasticity in a Mouse …

F Segovia‐Miranda, F Serrano, A Dyrda… - Arthritis & …, 2015 - Wiley Online Library
Objective To assess whether autoantibodies against ribosomal P (anti‐P), which are
possibly pathogenic in neuropsychiatric systemic lupus erythematosus (NPSLE), alter …