Epithelia are multiscale active liquid crystals

JM Armengol-Collado, LN Carenza, J Eckert… - Nature Physics, 2023 - nature.com
Biological processes such as embryogenesis, wound healing and cancer progression rely
on the ability of epithelial cells to coordinate their mechanical activity over length scales that …

Coupling of nematic in-plane orientational ordering and equilibrium shapes of closed flexible nematic shells

L Mesarec, W Góźdź, V Kralj-Iglič, S Kralj, A Iglič - Scientific reports, 2023 - nature.com
The impact of the intrinsic curvature of in-plane orientationally ordered curved flexible
nematic molecules attached to closed 3D flexible shells was studied numerically. A Helfrich …

Active transport in complex environments

A Martínez-Calvo, C Trenado-Yuste, SS Datta - 2023 - books.rsc.org
A key feature of many living systems, such as bacteria and eukaryotic cells, is their ability to
actively self-propel. Indeed, cellular motility underlies numerous critical biological …

Active topological defect absorption by a curvature singularity

F Vafa, DR Nelson… - Journal of Physics …, 2023 - iopscience.iop.org
Abstract We leverage the Born–Oppenheimer approximation to present a general
description of topological defects dynamics in p-atic materials on curved surfaces. Focusing …

Defect absorption and emission for -atic liquid crystals on cones

F Vafa, GH Zhang, DR Nelson - Physical Review E, 2022 - APS
We investigate the ground-state configurations of two-dimensional liquid crystals with p-fold
rotational symmetry (p-atics) on fixed curved surfaces. We focus on the intrinsic geometry …

From cell intercalation to flow, the importance of T1 transitions

HP Jain, A Voigt, L Angheluta - Physical Review Research, 2024 - APS
T1 transitions, also called cell intercalations, are important sources of fluidization of
epithelial cell monolayers. We use a multiphase field model to quantify this tissue fluidization …

Long-Ranged Order and Flow Alignment in Sheared ‐atic Liquid Crystals

L Giomi, J Toner, N Sarkar - Physical Review Letters, 2022 - APS
We formulate a hydrodynamic theory of p-atic liquid crystals, namely, two-dimensional
anisotropic fluids endowed with generic p-fold rotational symmetry. Our approach, based on …

Supramolecular assemblies in active motor-filament systems: micelles, bilayers, and foams

F De Luca, I Maryshev, E Frey - Physical Review X, 2024 - APS
Active matter systems evade the constraints of thermal equilibrium, leading to the
emergence of intriguing collective behavior. A paradigmatic example is given by motor …

Hydrodynamics and multiscale order in confluent epithelia

JM Armengol-Collado, LN Carenza, L Giomi - Elife, 2024 - elifesciences.org
We formulate a hydrodynamic theory of confluent epithelia: ie monolayers of epithelial cells
adhering to each other without gaps. Taking advantage of recent progresses toward …

Statics and diffusive dynamics of surfaces driven by p-atic topological defects

F Vafa, L Mahadevan - Soft Matter, 2023 - pubs.rsc.org
Inspired by epithelial morphogenesis, we consider a minimal model for the sha** of a
surface driven by p-atic topological defects. We show that a positive (negative) defect can …