More than just attractive: how CCL2 influences myeloid cell behavior beyond chemotaxis

M Gschwandtner, R Derler, KS Midwood - Frontiers in immunology, 2019 - frontiersin.org
Monocyte chemoattractant protein-1 (MCP-1/CCL2) is renowned for its ability to drive the
chemotaxis of myeloid and lymphoid cells. It orchestrates the migration of these cell types …

Monocyte Chemoattractant Protein 1 (MCP-1) in obesity and diabetes

J Panee - Cytokine, 2012 - Elsevier
Monocyte Chemoattractant Protein-1 (MCP-1) is the first discovered and most extensively
studied CC chemokine, and the amount of studies on its role in the etiologies of obesity-and …

The wide utility of rabbits as models of human diseases

PJ Esteves, J Abrantes, HM Baldauf… - … & molecular medicine, 2018 - nature.com
Studies using the European rabbit Oryctolagus cuniculus contributed to elucidating
numerous fundamental aspects of antibody structure and diversification mechanisms and …

Chemokine: receptor structure, interactions, and antagonism

SJ Allen, SE Crown, TM Handel - Annu. Rev. Immunol., 2007 - annualreviews.org
Chemokines are critical mediators of cell migration during routine immune surveillance,
inflammation, and development. Chemokines bind to G protein–coupled receptors and …

Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-α and leaves RANTES and MCP …

PE Van den Steen, P Proost, A Wuyts… - Blood, The Journal …, 2000 - ashpublications.org
Chemokines are mediators in inflammatory and autoimmune disorders. Aminoterminal
truncation of chemokines results in altered specific activities and receptor recognition …

Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo

GA McQuibban, JH Gong, JP Wong… - Blood, The Journal …, 2002 - ashpublications.org
Monocyte chemoattractant protein (MCP)–3 is inactivated upon cleavage by the matrix
metalloproteinase (MMP) gelatinase A (MMP-2). We investigated the susceptibility to …

The MCP/eotaxin subfamily of CC chemokines

E Van Coillie, J Van Damme, G Opdenakker - Cytokine & growth factor …, 1999 - Elsevier
Migration of leukocytes from the bone marrow to the circulation, the primary lymphoid organs
and inflammatory sites is directed by chemokines and specific receptor interactions. Besides …

The multifunctional or moonlighting protein CD26/DPPIV

E Boonacker, CJF Van Noorden - European journal of cell biology, 2003 - Elsevier
CD26/DPPIV can be considered a moonlighting protein because it is a multifunctional
protein that exerts its different functions depending on cell type and intra-or extracellular …

CD26: a multifunctional integral membrane and secreted protein of activated lymphocytes

MD Gorrell, V Gysbers… - Scandinavian journal of …, 2001 - Wiley Online Library
CD26 has proved interesting in the fields of immunology, endocrinology, cancer biology and
nutrition owing to its ubiquitous and unusual enzyme activity. This dipeptidyl …

Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent manner

M Rafei, PM Campeau, A Aguilar-Mahecha… - The Journal of …, 2009 - journals.aai.org
The administration of ex vivo culture-expanded mesenchymal stromal cells (MSCs) has
been shown to reverse symptomatic neuroinflammation observed in experimental …