Obesity phenotypes, diabetes, and cardiovascular diseases
This review addresses the interplay between obesity, type 2 diabetes mellitus, and
cardiovascular diseases. It is proposed that obesity, generally defined by an excess of body …
cardiovascular diseases. It is proposed that obesity, generally defined by an excess of body …
Obesity and type 2 diabetes mellitus: connections in epidemiology, pathogenesis, and treatments
R Ruze, T Liu, X Zou, J Song, Y Chen, R Xu… - Frontiers in …, 2023 - frontiersin.org
The prevalence of obesity and diabetes mellitus (DM) has been consistently increasing
worldwide. Sharing powerful genetic and environmental features in their pathogenesis …
worldwide. Sharing powerful genetic and environmental features in their pathogenesis …
Obesity and cancer risk: Emerging biological mechanisms and perspectives
Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …
[HTML][HTML] Human gut microbiome: hopes, threats and promises
PD Cani - Gut, 2018 - gut.bmj.com
The microbiome has received increasing attention over the last 15 years. Although gut
microbes have been explored for several decades, investigations of the role of …
microbes have been explored for several decades, investigations of the role of …
The intestinal microbiota fuelling metabolic inflammation
Low-grade inflammation is the hallmark of metabolic disorders such as obesity, type 2
diabetes and nonalcoholic fatty liver disease. Emerging evidence indicates that these …
diabetes and nonalcoholic fatty liver disease. Emerging evidence indicates that these …
Microbiota succession throughout life from the cradle to the grave
Associations between age and the human microbiota are robust and reproducible. The
microbial composition at several body sites can predict human chronological age relatively …
microbial composition at several body sites can predict human chronological age relatively …
Bacterial sensing via neuronal Nod2 regulates appetite and body temperature
I Gabanyi, G Lepousez, R Wheeler, A Vieites-Prado… - Science, 2022 - science.org
Gut bacteria influence brain functions and metabolism. We investigated whether this
influence can be mediated by direct sensing of bacterial cell wall components by brain …
influence can be mediated by direct sensing of bacterial cell wall components by brain …
Gut microbiota as a trigger for metabolic inflammation in obesity and type 2 diabetes
TPM Scheithauer, E Rampanelli, M Nieuwdorp… - Frontiers in …, 2020 - frontiersin.org
The gut microbiota has been linked to the development of obesity and type 2 diabetes (T2D).
The underlying mechanisms as to how intestinal microbiota may contribute to T2D are only …
The underlying mechanisms as to how intestinal microbiota may contribute to T2D are only …
Peptidoglycan recognition by the innate immune system
AJ Wolf, DM Underhill - Nature Reviews Immunology, 2018 - nature.com
The innate immune system recognizes microbial products using germline-encoded
receptors that initiate inflammatory responses to infection. The bacterial cell wall component …
receptors that initiate inflammatory responses to infection. The bacterial cell wall component …
Influence of high-fat diet on gut microbiota: a driving force for chronic disease risk
EA Murphy, KT Velazquez… - Current Opinion in Clinical …, 2015 - journals.lww.com
Influence of high-fat diet on gut microbiota: a driving forc... : Current Opinion in Clinical
Nutrition & Metabolic Care Influence of high-fat diet on gut microbiota: a driving force for …
Nutrition & Metabolic Care Influence of high-fat diet on gut microbiota: a driving force for …