Subcellular visualization: organelle-specific targeted drug delivery and discovery

X Shao, C Meng, W Song, T Zhang, Q Chen - Advanced Drug Delivery …, 2023 - Elsevier
Organelles perform critical biological functions due to their distinct molecular composition
and internal environment. Disorders in organelles or their interacting networks have been …

Single-organelle localization-based super-resolution imaging for subcellular molecules micro-dynamics

G Fang, D Liu, M Zhang, L Shao, X Shao… - Coordination Chemistry …, 2024 - Elsevier
Combining probes with advanced imaging techniques has enabled single-organelle
localization-based super-resolution imaging, revolutionizing our ability to investigate …

Red emissive carbon dots as a fluorescent sensor for fast specific monitoring and imaging of polarity in living cells

Z Yang, H Li, T Xu, M She, J Chen, X Jia… - Journal of Materials …, 2023 - pubs.rsc.org
Polarity is an integral microenvironment parameter, which is crucial for establishing and
reflecting a large number of sophisticated physiological functions and pathological effects …

Advanced imaging techniques for tracking drug dynamics at the subcellular level

C Zhang, Z Tian, R Chen, F Rowan, K Qiu… - Advanced drug delivery …, 2023 - Elsevier
Optical microscopes are an important imaging tool that have effectively advanced the
development of modern biomedicine. In recent years, super-resolution microscopy (SRM) …

Molecular probes for super-resolution imaging of drug dynamics

H Fang, M Wang, P Wei, Q Liu, Y Su, H Liu… - Advanced Drug Delivery …, 2024 - Elsevier
Super-resolution molecular probes (SRMPs) are essential tools for visualizing drug
dynamics within cells, transcending the resolution limits of conventional microscopy. In this …

Super-resolution fluorescence microscopic imaging in pathogenesis and drug treatment of neurological disease

J Gong, Z **, H Chen, J He, Y Zhang… - Advanced Drug Delivery …, 2023 - Elsevier
Since super-resolution fluorescence microscopic technology breaks the diffraction limit that
has existed for a long time in optical imaging, it can observe the process of synapses formed …

Fluorogenic Probes for Functional Imaging of Endoplasmic Reticulum‐Resident Proteins: from Molecular Engineering to Biomedical Applications

Y Fan, F Zhang, Y Hao, L Chen, Q Zhou… - Advanced Functional …, 2024 - Wiley Online Library
Endoplasmic reticulum‐resident proteins (ERPs) are crucial for maintaining cellular
homeostasis and are tightly associated with the onset and progression of various diseases …