The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …
antibiotics are becoming less effective against these bacteria, such that we risk entering a …
Chemically modified and conjugated antimicrobial peptides against superbugs
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
Peptide design and self-assembly into targeted nanostructure and functional materials
Peptides have been extensively utilized to construct nanomaterials that display targeted
structure through hierarchical assembly. The self-assembly of both rationally designed …
structure through hierarchical assembly. The self-assembly of both rationally designed …
Biocompatible synthetic polymers for tissue engineering purposes
Z Terzopoulou, A Zamboulis, I Koumentakou… - …, 2022 - ACS Publications
Synthetic polymers have been an integral part of modern society since the early 1960s.
Besides their most well-known applications to the public, such as packaging, construction …
Besides their most well-known applications to the public, such as packaging, construction …
Recent advances in design of antimicrobial peptides and polypeptides toward clinical translation
The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …
Poly (ethylene glycol) alternatives in biomedical applications
X Yao, C Qi, C Sun, F Huo, X Jiang - Nano Today, 2023 - Elsevier
Abstract Poly (ethylene glycol)(PEG) as gold standard has been extensively conjugated to
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …
Charge reversal nano-systems for tumor therapy
P Zhang, D Chen, L Li, K Sun - Journal of Nanobiotechnology, 2022 - Springer
Surface charge of biological and medical nanocarriers has been demonstrated to play an
important role in cellular uptake. Owing to the unique physicochemical properties, charge …
important role in cellular uptake. Owing to the unique physicochemical properties, charge …
pH-Sensitive nanogels for drug delivery in cancer therapy
Z Li, J Huang, J Wu - Biomaterials Science, 2021 - pubs.rsc.org
As a commonly used treatment method for cancer, chemotherapy is greatly limited by the
side effects of chemotherapy drugs and the multiple drug resistance that develops …
side effects of chemotherapy drugs and the multiple drug resistance that develops …
Intelligent poly (l-histidine)-based nanovehicles for controlled drug delivery
Stimuli-responsive drug delivery systems based on polymeric nanovehicles are among the
most promising treatment regimens for malignant cancers. Such intelligent systems that …
most promising treatment regimens for malignant cancers. Such intelligent systems that …
Recent Advances and Future Developments in the Preparation of Polypeptides via N-Carboxyanhydride (NCA) Ring-Opening Polymerization
Polypeptides have the same or similar backbone structures as proteins and peptides,
rendering them as suitable and important biomaterials. Amino acid N-carboxyanhydrides …
rendering them as suitable and important biomaterials. Amino acid N-carboxyanhydrides …