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What goes up must come down: off switches for regulatory RNAs
K McJunkin, S Gottesman - Genes & Development, 2024 - genesdev.cshlp.org
Small RNAs base pair with and regulate mRNA translation and stability. For both bacterial
small regulatory RNAs and eukaryotic microRNAs, association with partner proteins is …
small regulatory RNAs and eukaryotic microRNAs, association with partner proteins is …
The Acid-Stimulated Self-Assembled DNA Nanonetwork for Sensitive Detection and Living Cancer Cell Imaging of MicroRNA-221
Y Han, M Jiang, J Zhou, H Lei, R Yuan… - Analytical …, 2024 - ACS Publications
Herein, a novel functional DNA structure, acid-stimulated self-assembly DNA nanonetwork
(ASDN), was proposed for miRNA-221 sensitive detection and high-resolution living cancer …
(ASDN), was proposed for miRNA-221 sensitive detection and high-resolution living cancer …
Widespread destabilization of Caenorhabditis elegans microRNAs by the E3 ubiquitin ligase EBAX-1
MicroRNAs (miRNAs) associate with Argonaute (AGO) proteins to form complexes that direct
mRNA repression. miRNAs are also the subject of regulation. For example, some miRNAs …
mRNA repression. miRNAs are also the subject of regulation. For example, some miRNAs …
In silico identification and characterization of microRNAs from rotifers, cladocerans, and copepods
MicroRNAs (miRNAs) are short non-coding RNA molecules that regulate post-transcription
and influence various biological processes across species. Despite various studies of …
and influence various biological processes across species. Despite various studies of …
Retargeting target-directed microRNA-decay sites to highly expressed viral or cellular miRNAs
JA Ortega, Z Liang, JK Xu, E Gottwein - Nucleic acids research, 2024 - academic.oup.com
MicroRNAs (miRNAs) are pervasive regulators of gene expression, necessitating the
development of tools to inhibit individual miRNAs for functional studies or therapeutic …
development of tools to inhibit individual miRNAs for functional studies or therapeutic …
An endogenous enzyme-gated DNA nanomachine for spatially controlled imaging of intracellular microRNA and in situ evaluation of drug response
L Li, S Xu, M Chen, P Lu, M Zhao, J Jiao… - Chemical Engineering …, 2025 - Elsevier
In situ imaging of tumor-associated microRNAs (miRNAs) is crucial for evaluating the risk of
tumor occurrence and progression. However, traditional biosensors face challenges such as …
tumor occurrence and progression. However, traditional biosensors face challenges such as …
Dora, a key component of target-directed miRNA degradation, is essential for local genomic amplification in Drosophila ovarian follicle cells
N Akulenko, O Olenkina, S Marfina, E Mikhaleva… - bioRxiv, 2025 - biorxiv.org
The ubiquitin ligase receptor Dora, the Drosophila homolog of ZSWIM8, is a key component
of the target-directed microRNA degradation (TDMD) pathway. Previous studies have …
of the target-directed microRNA degradation (TDMD) pathway. Previous studies have …