Overview of microRNA biogenesis, mechanisms of actions, and circulation
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
Obesity and dyslipidemia
J Vekic, A Zeljkovic, A Stefanovic, Z Jelic-Ivanovic… - Metabolism, 2019 - Elsevier
Obesity, a pandemic of the modern world, is intimately associated with dyslipidemia, which
is mainly driven by the effects of insulin resistance and pro-inflammatory adipokines …
is mainly driven by the effects of insulin resistance and pro-inflammatory adipokines …
Exosome and exosomal microRNA: trafficking, sorting, and function
J Zhang, S Li, L Li, M Li, C Guo, J Yao… - Genomics, Proteomics …, 2015 - academic.oup.com
Abstract Exosomes are 40–100 nm nano-sized vesicles that are released from many cell
types into the extracellular space. Such vesicles are widely distributed in various body fluids …
types into the extracellular space. Such vesicles are widely distributed in various body fluids …
[HTML][HTML] The role of lipids and lipoproteins in atherosclerosis
MRF Linton, PG Yancey, SS Davies, WG Jerome… - Endotext …, 2019 - ncbi.nlm.nih.gov
Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …
A comparative study of serum exosome isolation using differential ultracentrifugation and three commercial reagents
Exosomes play a role in cell-to-cell signaling and serve as possible biomarkers. Isolating
exosomes with reliable quality and substantial concentration is a major challenge. Our …
exosomes with reliable quality and substantial concentration is a major challenge. Our …
MicroRNAs in cardiovascular disease
Micro-ribonucleic acids (miRNAs) are in the spotlight as post-transcriptional regulators of
gene expression. More than 1,000 miRNAs are encoded in the human genome. In this …
gene expression. More than 1,000 miRNAs are encoded in the human genome. In this …
Cell‐to‐cell communication: microRNAs as hormones
Mammalian cells can release different types of extracellular vesicles (EVs), including
exosomes, microvesicles, and apoptotic bodies. Accumulating evidence suggests that EVs …
exosomes, microvesicles, and apoptotic bodies. Accumulating evidence suggests that EVs …
[HTML][HTML] Extracellular/circulating microRNAs: release mechanisms, functions and challenges
MH Sohel - Achievements in the Life Sciences, 2016 - Elsevier
MicroRNAs (miRNAs) are endogenously initiated, small non-coding RNAs and typically
regulate the expression of mRNAs in post transcriptional level either via translational …
regulate the expression of mRNAs in post transcriptional level either via translational …
What is the blood concentration of extracellular vesicles? Implications for the use of extracellular vesicles as blood-borne biomarkers of cancer
Circulating biomarkers have a great potential in diagnosing cancer diseases at early stages,
where curative treatment is a realistic possibility. In the recent years, using extracellular …
where curative treatment is a realistic possibility. In the recent years, using extracellular …
Neutrophil-to-hepatocyte communication via LDLR-dependent miR-223–enriched extracellular vesicle transfer ameliorates nonalcoholic steatohepatitis
Neutrophil infiltration around lipotoxic hepatocytes is a hallmark of nonalcoholic
steatohepatitis (NASH); however, how these 2 types of cells communicate remains obscure …
steatohepatitis (NASH); however, how these 2 types of cells communicate remains obscure …