The Association between CCL5/RANTES SNPs and Susceptibility to HIV-1 Infection: A Meta-Analysis

MJA Silva, RL Marinho, PAS Dos Santos… - Viruses, 2023 - mdpi.com
Genetic polymorphisms in genes that encode natural ligands of CCR5 (the main human HIV
coreceptor), such as CCL5/RANTES, can alter the levels of secretion of these peptides. This …

The CCL2/CCR2 axis in the pathogenesis of HIV-1 infection: a new cellular target for therapy?

D Angela Covino, M Sabbatucci… - Current drug targets, 2016 - ingentaconnect.com
The identification of chemokine receptors as necessary co-receptors for HIV entry into target
cells represented a breakthrough in the understanding of the pathogenesis of this viral …

Host factors and HIV-1 replication: clinical evidence and potential therapeutic approaches

M Santa-Marta, PM de Brito, A Godinho-Santos… - Frontiers in …, 2013 - frontiersin.org
HIV and human defense mechanisms have co-evolved to counteract each other. In the
process of infection, HIV takes advantage of cellular machinery and blocks the action of the …

Genetic determinants of HIV‐1 infection and progression to AIDS: susceptibility to HIV infection

G Kaur, N Mehra - Tissue antigens, 2009 - Wiley Online Library
Interindividual variability in susceptibility to HIV‐1 infection, its transmission, disease
progression, and response to antiviral therapy has been attributed to host determinants and …

Immunogenetics of HIV and HIV associated tuberculosis

S Raghavan, K Alagarasu, P Selvaraj - Tuberculosis, 2012 - Elsevier
Tuberculosis (TB) is the frequent major opportunistic infection in HIV-infected patients, and is
the leading cause of mortality among HIV-infected patients. Genetic susceptibility to TB in …

Immunogenetic basis of HIV-1 infection, transmission and disease progression

P Singh, G Kaur, G Sharma, NK Mehra - Vaccine, 2008 - Elsevier
Susceptibility to HIV-1 infection and rate of disease progression to AIDS are complex traits
modulated by environmental and genetic factors. Studies on large AIDS cohorts and their …

Genetic polymorphisms of CCL2, CCL5, CCR2 and CCR5 genes in Sahariya tribe of North Central India: an association study with pulmonary tuberculosis

G Mishra, SS Poojary, P Raj, PK Tiwari - Infection, Genetics and Evolution, 2012 - Elsevier
The association of genetic variants of chemokines, CCL2 [MCP-1 (monocyte
chemoattractant protein-1)], CCL5 [RANTES (regulated on activation, normal T-cell …

CCL5 (RANTES) gene polymorphisms in pulmonary tuberculosis patients of south India

P Selvaraj, K Alagarasu, B Singh… - International journal of …, 2011 - Wiley Online Library
The chemokine CCL5 is known to play an important role in the formation of granuloma
during infection with Mycobacterium tuberculosis. Production of CCL5 is influenced by …

Gene polymorphisms in CCR5, CCR2, SDF1 and RANTES among Chinese Han population with HIV-1 infection

H Li, TJ Liu, ZH Hong - Infection, Genetics and Evolution, 2014 - Elsevier
Chemokines and chemokine receptors are crucial for immune response in HIV-1 infection.
Although many studies have been done to investigate the relationship between chemokines …

Chemokines and chemokine receptors in susceptibility to HIV-1 infection and progression to AIDS

A Chatterjee, A Rathore, S Vidyant, K Kakkar… - Disease …, 2012 - content.iospress.com
A multitude of host genetic factors plays a crucial role in susceptibility to HIV-1 infection and
progression to AIDS, which is highly variable among individuals and populations. This …