The actin cytoskeleton in memory formation
R Lamprecht - Progress in neurobiology, 2014 - Elsevier
The ability to efficiently store memories in the brain is a fundamental process and its
impairment is associated with multiple human mental disorders. Evidence indicates that long …
impairment is associated with multiple human mental disorders. Evidence indicates that long …
Modulation of actin dynamics by Rac1 to target cognitive function
MV Tejada‐Simon - Journal of neurochemistry, 2015 - Wiley Online Library
The small GTP ase Rac1 is well known for regulating actin cytoskeleton reorganization in
cells. Formation of extensions at the surface of the cell is required for migration and even for …
cells. Formation of extensions at the surface of the cell is required for migration and even for …
Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities
Despite evidence for a strong genetic contribution to several major psychiatric disorders,
individual candidate genes account for only a small fraction of these disorders, leading to …
individual candidate genes account for only a small fraction of these disorders, leading to …
Spine pruning drives antipsychotic-sensitive locomotion via circuit control of striatal dopamine
Psychiatric and neurodevelopmental disorders may arise from anomalies in long-range
neuronal connectivity downstream of pathologies in dendritic spines. However, the …
neuronal connectivity downstream of pathologies in dendritic spines. However, the …
Loss of Cdc42 leads to defects in synaptic plasticity and remote memory recall
Cdc42 is a signaling protein important for reorganization of actin cytoskeleton and
morphogenesis of cells. However, the functional role of Cdc42 in synaptic plasticity and in …
morphogenesis of cells. However, the functional role of Cdc42 in synaptic plasticity and in …
Regulation of immune cell development through soluble inositol-1, 3, 4, 5-tetrakisphosphate
K Sauer, MP Cooke - Nature Reviews Immunology, 2010 - nature.com
Abstract The membrane lipid phosphatidylinositol-3, 4, 5-trisphosphate (PtdInsP3) regulates
membrane receptor signalling in many cells, including immunoreceptor signalling. Here, we …
membrane receptor signalling in many cells, including immunoreceptor signalling. Here, we …
Presynaptic Rac1 in the hippocampus selectively regulates working memory
J Kim, E Bustamante, P Sotonyi, N Maxwell… - Elife, 2024 - elifesciences.org
One of the most extensively studied members of the Ras superfamily of small GTPases,
Rac1 is an intracellular signal transducer that remodels actin and phosphorylation signaling …
Rac1 is an intracellular signal transducer that remodels actin and phosphorylation signaling …
Stress‐Sensitive Protein Rac1 and Its Involvement in Neurodevelopmental Disorders
X Wang, D Liu, F Wei, Y Li, X Wang, L Li… - Neural …, 2020 - Wiley Online Library
Ras‐related C3 botulinum toxin substrate 1 (Rac1) is a small GTPase that is well known for
its sensitivity to the environmental stress of a cell or an organism. It senses the external …
its sensitivity to the environmental stress of a cell or an organism. It senses the external …
Lipid signaling in T-cell development and function
YH Huang, K Sauer - Cold Spring Harbor perspectives …, 2010 - cshperspectives.cshlp.org
Second messenger molecules relay, amplify, and diversify cell surface receptor signals. Two
important examples are phosphorylated D-myo-inositol derivatives, such as …
important examples are phosphorylated D-myo-inositol derivatives, such as …
Stimulation of MMP‐1 and CCL2 by NAMPT in PDL cells
M Nokhbehsaim, S Eick, AVB Nogueira… - Mediators of …, 2013 - Wiley Online Library
Periodontitis is an inflammatory disease caused by pathogenic microorganisms and
characterized by the destruction of the periodontium. Obese individuals have an increased …
characterized by the destruction of the periodontium. Obese individuals have an increased …