Trajectories toward risk or resilience in psychiatric disorders are influenced by acquired and
inherited factors. More recently, evidence from rodent studies suggest that acquired risk …

The striatum is a critical component of the brain that controls motor, reward, and executive
function. This ancient and phylogenetically conserved structure forms a central hub where …

Parkinson's disease (PD) is primarily associated with the degeneration of midbrain
dopamine neurons, but it is now appreciated that pathological processes like Lewy-body …

Long-term cognitive and neuropsychiatric outcomes of anti-gamma-aminobutyric-acid B
receptor (anti-GABA BR) encephalitis are unclear. In this prospective study, 31 patients with …

Locomotion and cue-dependent behaviors are modified through corticostriatal signaling
whereby short-term increases in dopamine availability can provoke persistent changes in …

Although many reviews exist characterizing the molecular differences of GABA B receptor
isoforms, there is no current review of the in vivo effects of these isoforms. The current review …

Background Prenatal cocaine exposure (PCE) is associated with increased rates of illicit-
substance use during adolescence. In addition, both PCE and illicit-substance use are …

Preclinical research has demonstrated the effects of prenatal cocaine exposure (PCE) on
brain regions involved in emotional regulation, motivational control, and addiction …

Abstract Effects of environmental factors may be transmitted to the following generation, and
cause neuropsychiatric disorders including depression, anxiety, and posttraumatic stress …

The GABAA receptor mediates fast, inhibitory signaling, and cortical expression of the α1
subunit increases during postnatal development. Certain pathological stimuli such as …