Obesity-associated breast cancer: analysis of risk factors

A Engin - Obesity and lipotoxicity, 2017 - Springer
Several studies show that a significantly stronger association is obvious between increased
body mass index (BMI) and higher breast cancer incidence. Furthermore, obese women are …

Stearoyl CoA desaturase-1: New insights into a central regulator of cancer metabolism

RA Igal - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2016 - Elsevier
The processes of cell proliferation, cell death and differentiation involve an intricate array of
biochemical and morphological changes that require a finely tuned modulation of metabolic …

Deep learning accurately predicts estrogen receptor status in breast cancer metabolomics data

FM Alakwaa, K Chaudhary… - Journal of proteome …, 2018 - ACS Publications
Metabolomics holds the promise as a new technology to diagnose highly heterogeneous
diseases. Conventionally, metabolomics data analysis for diagnosis is done using various …

Phasor S-FLIM: a new paradigm for fast and robust spectral fluorescence lifetime imaging

L Scipioni, A Rossetta, G Tedeschi, E Gratton - Nature methods, 2021 - nature.com
Fluorescence lifetime imaging microscopy (FLIM) and spectral imaging are two broadly
applied methods for increasing dimensionality in microscopy. However, their combination is …

Oleic acid induces apoptosis and autophagy in the treatment of Tongue Squamous cell carcinomas

L Jiang, W Wang, Q He, Y Wu, Z Lu, J Sun, Z Liu… - Scientific reports, 2017 - nature.com
Oleic acid (OA), a main ingredient of Brucea javanica oil (BJO), is widely known to have
anticancer effects in many tumors. In this study, we investigated the anticancer effect of OA …

Application of desorption electrospray ionization mass spectrometry imaging in breast cancer margin analysis

D Calligaris, D Caragacianu, X Liu, I Norton… - Proceedings of the …, 2014 - pnas.org
Distinguishing tumor from normal glandular breast tissue is an important step in breast-
conserving surgery. Because this distinction can be challenging in the operative setting, up …

Targeting fatty acid oxidation to promote anoikis and inhibit ovarian cancer progression

BT Sawyer, L Qamar, TM Yamamoto… - Molecular Cancer …, 2020 - aacrjournals.org
Epithelial-derived high-grade serous ovarian cancer (HGSOC) is the deadliest gynecologic
malignancy. Roughly 80% of patients are diagnosed with late-stage disease, which is …

Obesity and breast cancer: current insights on the role of fatty acids and lipid metabolism in promoting breast cancer growth and progression

C Blücher, SC Stadler - Frontiers in endocrinology, 2017 - frontiersin.org
Obesity and excess accumulation of adipose tissue are known risk factors for several types
of cancer, including breast cancer. With the incidence of obesity constantly rising worldwide …

Influence of olive oil and its components on breast cancer: Molecular mechanisms

R Moral, E Escrich - Molecules, 2022 - mdpi.com
Breast cancer is the most frequent malignant neoplasia and a leading cause of mortality in
women worldwide. The Mediterranean diet has been proposed as a healthy dietary pattern …

Migration of MDA-MB-231 breast cancer cells depends on the availability of exogenous lipids and cholesterol esterification

CJ Antalis, A Uchida, KK Buhman… - Clinical & experimental …, 2011 - Springer
We previously described a lipid-accumulating phenotype of estrogen receptor negative
(ER−) breast cancer cells exemplified by the MDA-MB-231 and MDA-MB-436 cell lines …