ALCAM/CD166: A pleiotropic mediator of cell adhesion, stemness and cancer progression
Abstract Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) is a glycoprotein
involved in homotypic and heterotypic cell adhesion. ALCAM can be proteolytically cleaved …
involved in homotypic and heterotypic cell adhesion. ALCAM can be proteolytically cleaved …
The functions and regulatory pathways of S100A8/A9 and its receptors in cancers
H Zhou, C Zhao, R Shao, Y Xu, W Zhao - Frontiers in Pharmacology, 2023 - frontiersin.org
Inflammation primarily influences the initiation, progression, and deterioration of many
human diseases, and immune cells are the principal forces that modulate the balance of …
human diseases, and immune cells are the principal forces that modulate the balance of …
Modified bovine milk exosomes for doxorubicin delivery to triple-negative breast cancer cells
Biological nanoparticles, such as exosomes, offer an approach to drug delivery because of
their innate ability to transport biomolecules. Exosomes are derived from cells and an …
their innate ability to transport biomolecules. Exosomes are derived from cells and an …
Cellular stress response to extremely low‐frequency electromagnetic fields (ELF‐EMF): An explanation for controversial effects of ELF‐EMF on apoptosis
Impaired apoptosis is one of the hallmarks of cancer, and almost all of the non‐surgical
approaches of eradicating tumour cells somehow promote induction of apoptosis. Indeed …
approaches of eradicating tumour cells somehow promote induction of apoptosis. Indeed …
Current status and future challenges of CAR-T cell therapy for osteosarcoma
S Li, H Zhang, G Shang - Frontiers in Immunology, 2023 - frontiersin.org
Osteosarcoma, the most common bone malignancy in children and adolescents, poses
considerable challenges in terms of prognosis, especially for patients with metastatic or …
considerable challenges in terms of prognosis, especially for patients with metastatic or …
Antibody-drug conjugates: Resurgent anticancer agents with multi-targeted therapeutic potential
Antibody–drug conjugates (ADCs) constitute a relatively new group of anticancer agents,
whose first appearance took place about two decades ago, but a renewed interest occurred …
whose first appearance took place about two decades ago, but a renewed interest occurred …
hTERT-immortalized mesenchymal stem cell-derived extracellular vesicles: large-scale manufacturing, cargo profiling, and functional effects in retinal epithelial cells
As the economic burden associated with vision loss and ocular damage continues to rise,
there is a need to explore novel treatment strategies. Extracellular vesicles (EVs) are …
there is a need to explore novel treatment strategies. Extracellular vesicles (EVs) are …
Blocking FSTL1 boosts NK immunity in treatment of osteosarcoma
Osteosarcoma (OS) is the most common primary bone malignancy. Many patients develop
relapse and metastasis after treatments, and more effective treatments are needed for …
relapse and metastasis after treatments, and more effective treatments are needed for …
Reciprocal interaction with neutrophils facilitates cutaneous accumulation of liposomes
T Ding, Y Wang, Y Meng, E Wu, Q Shao, S Lin, Y Yu… - ACS …, 2024 - ACS Publications
Liposomes are versatile drug delivery systems in clinical use for cancer and many other
diseases. Unfortunately, PEGylated liposomal doxorubicin (sLip/DOX) exhibits serious dose …
diseases. Unfortunately, PEGylated liposomal doxorubicin (sLip/DOX) exhibits serious dose …
[HTML][HTML] ALCAM/CD166 is involved in the binding and uptake of cancer-derived extracellular vesicles
B Cardeñes, I Clares, T Bezos, V Toribio… - International Journal of …, 2022 - mdpi.com
Colorectal cancer (CRC) and ovarian cancer (OvC) patients frequently develop peritoneal
metastasis, a condition associated with a very poor prognosis. In these cancers, tumor …
metastasis, a condition associated with a very poor prognosis. In these cancers, tumor …