Biochemistry and biophysics of HIV-1 gp41-membrane interactions and implications for HIV-1 envelope protein mediated viral-cell fusion and fusion inhibitor design
L Cai, M Gochin, K Liu - Current topics in medicinal chemistry, 2011 - ingentaconnect.com
Human immunodeficiency virus type 1 (HIV-1), the pathogen of acquired immunodeficiency
syndrome (AIDS), causes∼ 2 millions death every year and still defies an effective vaccine …
syndrome (AIDS), causes∼ 2 millions death every year and still defies an effective vaccine …
[HTML][HTML] Map** out the intricate relationship of the HIV envelope protein and the membrane environment
YA Klug, E Rotem, R Schwarzer, Y Shai - Biochimica et Biophysica Acta …, 2017 - Elsevier
The HIV gp160 envelope fusion protein is situated in the viral membrane and mediates virus
entry into its host cell. Increasing evidence suggests that virtually all parts of the HIV …
entry into its host cell. Increasing evidence suggests that virtually all parts of the HIV …
The computational route from bilayer membranes to vesicle fusion
Biological membranes are examples of'smart'materials whose properties and behaviour
emerge from the propagation across many scales of the molecular characteristics of their …
emerge from the propagation across many scales of the molecular characteristics of their …
Membranotropic effects of arbidol, a broad anti-viral molecule, on phospholipid model membranes
J Villalaín - The journal of physical chemistry B, 2010 - ACS Publications
Arbidol, a broad and potent antiviral molecule, incorporates rapidly into membranes. To gain
further insight into the mode of action of Arbidol, since the exact antiviral mechanism of …
further insight into the mode of action of Arbidol, since the exact antiviral mechanism of …
The membrane-active regions of the hepatitis C virus E1 and E2 envelope glycoproteins
We have identified the membrane-active regions of the full sequences of the HCV E1 and E2
envelope glycoproteins by performing an exhaustive study of membrane leakage …
envelope glycoproteins by performing an exhaustive study of membrane leakage …
[HTML][HTML] Membrane insertion of the three main membranotropic sequences from SARS-CoV S2 glycoprotein
J Guillén, PKJ Kinnunen, J Villalaín - Biochimica et Biophysica Acta (BBA) …, 2008 - Elsevier
In order to complete the fusion process of SARS-CoV virus, several regions of the S2 virus
envelope glycoprotein are necessary. Recent studies have identified three membrane-active …
envelope glycoprotein are necessary. Recent studies have identified three membrane-active …
A second SARS-CoV S2 glycoprotein internal membrane-active peptide. Biophysical characterization and membrane interaction
The severe acute respiratory syndrome coronavirus (SARS-CoV) envelope spike (S)
glycoprotein, a class I viral fusion protein, is responsible for the fusion between the …
glycoprotein, a class I viral fusion protein, is responsible for the fusion between the …
Peptides containing membrane-interacting motifs inhibit herpes simplex virus type 1 infectivity
S Galdiero, A Falanga, M Vitiello, M D'Isanto… - peptides, 2008 - Elsevier
Herpes simplex virus (HSV) membrane fusion represents an attractive target for anti-HSV
therapy. To investigate the structural basis of HSV membrane fusion and identify new targets …
therapy. To investigate the structural basis of HSV membrane fusion and identify new targets …
Conformational flexibility and strand arrangements of the membrane-associated HIV fusion peptide trimer probed by solid-state NMR spectroscopy
Z Zheng, R Yang, ML Bodner, DP Weliky - Biochemistry, 2006 - ACS Publications
The human immunodeficiency virus (HIV) fusion peptide (HFP) is the N-terminal apolar
region of the HIV gp41 fusion protein and interacts with target cell membranes and promotes …
region of the HIV gp41 fusion protein and interacts with target cell membranes and promotes …
Surface exposure of the HIV-1 env cytoplasmic tail LLP2 domain during the membrane fusion process: interaction with gp41 fusion core
HIV-1 gp41 cytoplasmic tail (CT) is highly conserved among HIV-1 isolates, particularly the
region designated lentivirus lytic peptide (LLP1–2), which includes two α-helical domains …
region designated lentivirus lytic peptide (LLP1–2), which includes two α-helical domains …