Novel isatin–triazole based thiosemicarbazones as potential anticancer agents: synthesis, DFT and molecular docking studies
Thiosemicarbazones of isatin have been found to exhibit versatile bioactivities. In this study,
two distinct types of isatin–triazole hybrids 3a and 3b were accessed via copper-catalyzed …
two distinct types of isatin–triazole hybrids 3a and 3b were accessed via copper-catalyzed …
5-Fluoro-1H-indole-2, 3-dione-triazoles-synthesis, biological activity, molecular docking, and DFT study
An environmental friendly heterogeneous catalyst Cell-CuI-NPs was employed for the
synthesis of biologically promising 1-((1-aryl)-1H-1, 2, 3-triazol-4-yl) methyl-5-fluoroindoline …
synthesis of biologically promising 1-((1-aryl)-1H-1, 2, 3-triazol-4-yl) methyl-5-fluoroindoline …
Synthesis, crystal structures, spectroscopic and nonlinear optical properties of chalcone derivatives: a combined experimental and theoretical study
A set of chalcone compounds were prepared by reacting p-bromoacetophenone with
various substituted aromatic aldehyde in ethanol using sodium ethoxide as base. The …
various substituted aromatic aldehyde in ethanol using sodium ethoxide as base. The …
Facile Ultrasound‐Based Synthesis, SC‐XRD, DFT Exploration of the Substituted Acyl‐Hydrazones: An Experimental and Theoretical Slant towards Supramolecular …
Sono‐chemical synthesis is safest and greener methods to fabricate valuable scaffolds in
short time. Currently, we are reporting an efficient ultrasound‐based synthesis of substituted …
short time. Currently, we are reporting an efficient ultrasound‐based synthesis of substituted …
Investigating the binding of organic charge transfer co-crystals to human serum albumin by experimental and theoretical methods: spectroscopy, molecular docking …
A new complex was formed by the transfer of charge between 2-ethylimidazole (2-EIM) as
an electron donor and 1, 2, 4, 5-benzenetetracarboxylic acid (BTC) as a π acceptor and …
an electron donor and 1, 2, 4, 5-benzenetetracarboxylic acid (BTC) as a π acceptor and …
Synthesis, structure elucidation, SC-XRD/DFT, molecular modelling simulations and DNA binding studies of 3,5-diphenyl-4,5-dihydro-1H-pyrazole chalcones
Deoxyribonucleic acid (DNA) acts as the most important intracellular target for various drugs.
Exploring the DNA binding interactions of small bioactive molecules offers a structural …
Exploring the DNA binding interactions of small bioactive molecules offers a structural …
Synthesis, characterization and biological evaluation of novel azo fused 2, 3-dihydro-1H-perimidine derivatives: In vitro antibacterial, antibiofilm, anti-quorum sensing …
N Nagasundaram, C Govindhan, S Sumitha… - Journal of Molecular …, 2022 - Elsevier
A catalyst-free efficient approach for the synthesis of a novel series of azo fused 2, 3-dihydro-
1H-perimidine scaffolds is described via one-pot cyclocondensation reactions of multifarious …
1H-perimidine scaffolds is described via one-pot cyclocondensation reactions of multifarious …
Synthesis of water-soluble novel bioactive pyridine-based azo coumarin derivative and competitive cytotoxicity, DNA binding, BSA binding study, and in silico analysis …
The diazo coupliling reaction of 3-amino pyridine with coumarin in water medium produces
water soluble 6-[3-pyridyl] azocoumarin. The synthesised compound has been fully …
water soluble 6-[3-pyridyl] azocoumarin. The synthesised compound has been fully …
Generic hapten synthesis, broad-specificity monoclonal antibodies preparation, and ultrasensitive ELISA for five antibacterial synergists in chicken and milk
An antibody with broad specificity and principally depending on hapten structure and size is
a key reagent for develo** a class-selective immunoassay. In the present study, three new …
a key reagent for develo** a class-selective immunoassay. In the present study, three new …
Development of epitopephore-based rational hapten design strategy: A combination of theoretical evidence and experimental validation
X Zhang, Y Bai, Q Tang, M Liu, L Nan, K Wen… - Journal of hazardous …, 2023 - Elsevier
Antibody is the key biomolecule that governing the sensitivity and specificity of an
immunoassay for chemical compound, also named hapten molecule. Obviously, predication …
immunoassay for chemical compound, also named hapten molecule. Obviously, predication …