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Production of secondary metabolites using tissue culture-based biotechnological applications
Plants are the sources of many bioactive secondary metabolites which are present in plant
organs including leaves, stems, roots, and flowers. Although they provide advantages to the …
organs including leaves, stems, roots, and flowers. Although they provide advantages to the …
Biosynthesis of monoterpenoid and sesquiterpenoid as natural flavors and fragrances
H Jiang, X Wang - Biotechnology Advances, 2023 - Elsevier
Terpenoids are a large class of plant-derived compounds, that constitute the main
components of essential oils and are widely used as natural flavors and fragrances. The …
components of essential oils and are widely used as natural flavors and fragrances. The …
Widespread biosynthesis of 16-carbon terpenoids in bacteria
YT Duan, A Koutsaviti, M Harizani, C Ignea… - Nature Chemical …, 2023 - nature.com
Terpenoids are the most diverse group of specialized metabolites with numerous
applications. Their biosynthesis is based on the five-carbon isoprene building block and, as …
applications. Their biosynthesis is based on the five-carbon isoprene building block and, as …
Engineering yeast for the production of plant terpenoids using synthetic biology approaches
Covering: 2011–2022 The low amounts of terpenoids produced in plants and the difficulty in
synthesizing these complex structures have stimulated the production of terpenoid …
synthesizing these complex structures have stimulated the production of terpenoid …
[HTML][HTML] Exploring the potent anticancer activity of essential oils and their bioactive compounds: Mechanisms and prospects for future cancer therapy
Cancer is one of the leading causes of death worldwide, affecting millions of people each
year. Fortunately, the last decades have been marked by considerable advances in the field …
year. Fortunately, the last decades have been marked by considerable advances in the field …
Synthetic biology advances towards a bio-based society in the era of artificial intelligence
Highlights•Artificial intelligence tools are emerging as valuable gears in synthetic
biology.•Plant-based products and technologies are key solutions for a bio-based …
biology.•Plant-based products and technologies are key solutions for a bio-based …
Expanding the structural diversity of terpenes by synthetic biology approaches
R Chen, M Wang, JD Keasling, T Hu, X Yin - Trends in Biotechnology, 2024 - cell.com
Terpenoids display chemical and structural diversities as well as important biological
activities. Despite their extreme variability, the range of these structures is limited by the …
activities. Despite their extreme variability, the range of these structures is limited by the …
A roadmap to establish a comprehensive platform for sustainable manufacturing of natural products in yeast
G Naseri - Nature Communications, 2023 - nature.com
Secondary natural products (NPs) are a rich source for drug discovery. However, the low
abundance of NPs makes their extraction from nature inefficient, while chemical synthesis is …
abundance of NPs makes their extraction from nature inefficient, while chemical synthesis is …
The Scent of Change: Sustainable fragrances through industrial biotechnology
F Michailidou - ChemBioChem, 2023 - Wiley Online Library
Current environmental and safety considerations urge innovation to address the need for
sustainable high‐value chemicals that are embraced by consumers. This review discusses …
sustainable high‐value chemicals that are embraced by consumers. This review discusses …
Non‐canonical Biosynthesis of the Brexane‐Type Bishomosesquiterpene Chlororaphen through Two Consecutive Methylation Steps in Pseudomonas chlororaphis …
N Magnus, SH von Reuss, F Braack… - Angewandte …, 2023 - Wiley Online Library
A non‐canonical biosynthetic pathway furnishing the first natural brexane‐type
bishomosesquiterpene (chlororaphen, C17H28) was elucidated in the γ‐proteobacterium …
bishomosesquiterpene (chlororaphen, C17H28) was elucidated in the γ‐proteobacterium …