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Transformer-based deep learning for predicting protein properties in the life sciences
Recent developments in deep learning, coupled with an increasing number of sequenced
proteins, have led to a breakthrough in life science applications, in particular in protein …
proteins, have led to a breakthrough in life science applications, in particular in protein …
Integrating multi-omics to unravel host-microbiome interactions in inflammatory bowel disease
The gut microbiome is crucial for nutrient metabolism, immune regulation, and intestinal
homeostasis with changes in its composition linked to complex diseases like inflammatory …
homeostasis with changes in its composition linked to complex diseases like inflammatory …
Ensembl 2024
Abstract Ensembl (https://www. ensembl. org) is a freely available genomic resource that has
produced high-quality annotations, tools, and services for vertebrates and model organisms …
produced high-quality annotations, tools, and services for vertebrates and model organisms …
STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
Proteins and their functional interactions form the backbone of the cellular machinery. Their
connectivity network needs to be considered for the full understanding of biological …
connectivity network needs to be considered for the full understanding of biological …
LSTM-PHV: prediction of human-virus protein–protein interactions by LSTM with word2vec
Viral infection involves a large number of protein–protein interactions (PPIs) between human
and virus. The PPIs range from the initial binding of viral coat proteins to host membrane …
and virus. The PPIs range from the initial binding of viral coat proteins to host membrane …
[HTML][HTML] Prediction of human-virus protein-protein interactions through a sequence embedding-based machine learning method
The identification of human-virus protein-protein interactions (PPIs) is an essential and
challenging research topic, potentially providing a mechanistic understanding of viral …
challenging research topic, potentially providing a mechanistic understanding of viral …
Viruses. STRING: a virus-host protein-protein interaction database
As viruses continue to pose risks to global health, having a better understanding of virus–
host protein–protein interactions aids in the development of treatments and vaccines. Here …
host protein–protein interactions aids in the development of treatments and vaccines. Here …
Protein–protein interactions in virus–host systems
To study virus–host protein interactions, knowledge about viral and host protein
architectures and repertoires, their particular evolutionary mechanisms, and information on …
architectures and repertoires, their particular evolutionary mechanisms, and information on …
Medicinal chemistry strategies toward host targeting antiviral agents
Direct‐acting antiviral agents (DAAs) represent a class of drugs targeting viral proteins and
have been demonstrated to be very successful in combating viral infections in clinic …
have been demonstrated to be very successful in combating viral infections in clinic …
The psychiatric cell map initiative: a convergent systems biological approach to illuminating key molecular pathways in neuropsychiatric disorders
Although gene discovery in neuropsychiatric disorders, including autism spectrum disorder,
intellectual disability, epilepsy, schizophrenia, and Tourette disorder, has accelerated …
intellectual disability, epilepsy, schizophrenia, and Tourette disorder, has accelerated …