Role of monoamine oxidase activity in Alzheimer's disease: an insight into the therapeutic potential of inhibitors

T Behl, D Kaur, A Sehgal, S Singh, N Sharma… - Molecules, 2021 - mdpi.com
Despite not being utilized as considerably as other antidepressants in the therapy of
depression, the monoamine oxidase inhibitors (MAOIs) proceed to hold a place in …

Metabolism and pharmacological activities of the natural health-benefiting compound diosmin

Y Zheng, R Zhang, W Shi, L Li, H Liu, Z Chen, L Wu - Food & function, 2020 - pubs.rsc.org
Diosmin is a famous natural flavonoid for treating chronic venous insufficiency and varicose
veins. Recently, extensive study has indicated that diosmin possesses diverse …

Lentinan inhibits oxidative stress and alleviates LPS-induced inflammation and apoptosis of BMECs by activating the Nrf2 signaling pathway

M Meng, R Huo, Y Wang, N Ma, X Shi, X Shen… - International Journal of …, 2022 - Elsevier
Lentinan (LNT) has been reported to have a wide range of functions, including anti-
inflammatory, antioxidant and anticancer properties. LNT may provide a protective effect in …

The protective effects of hesperidin and curcumin on 5-fluorouracil–induced nephrotoxicity in mice

V Gelen, E Şengül, S Yıldırım, E Senturk… - … Science and Pollution …, 2021 - Springer
Nephrotoxicity is a very important complication of 5-fluorouracil (5-FU)–treated cancer
patients. Increased oxidative stress, kidney damage, and apoptosis play an important role in …

Diosmin alleviates doxorubicin-induced liver injury via modulation of oxidative stress-mediated hepatic inflammation and apoptosis via NfkB and MAPK pathway: A …

AF AlAsmari, M Alharbi, F Alqahtani, F Alasmari… - Antioxidants, 2021 - mdpi.com
Hepatotoxicity caused by chemotherapeutic drugs (eg, doxorubicin) is of critical concern in
cancer therapy. This study focused on investigating the modulatory effects of diosmin …

Pharmacology of diosmin, a citrus flavone glycoside: an updated review

SH Gerges, SA Wahdan, DA Elsherbiny… - European journal of …, 2022 - Springer
Flavonoids are phytochemicals that are well known for their beneficial pharmacological
properties. Diosmin is a flavone glycoside derived from hesperidin, a flavanone abundantly …

The anti-inflammatory, anti-apoptotic, and antioxidant effects of a pomegranate-peel extract against acrylamide-induced hepatotoxicity in rats

S Sayed, SS Alotaibi, AM El-Shehawi, MM Hassan… - Life, 2022 - mdpi.com
The Acrylamide is a toxic compound generated under oxidative stress arising from
intracellular ROS production and induced toxicity. It is frequently used in industry and …

Morin protects against acrylamide-induced neurotoxicity in rats: an investigation into different signal pathways

C Gur, FM Kandemir, E Darendelioglu… - … Science and Pollution …, 2021 - Springer
The presented study investigates the effects of morin against toxicity induced by acrylamide
(ACR) in the brains of Sprague Dawley rats. In this study, neurotoxicity was induced by orally …

Acrylamide-induced peripheral neuropathy: manifestations, mechanisms, and potential treatment modalities

M Bin-Jumah, AFM Abdel-Fattah, EM Saied… - … Science and Pollution …, 2021 - Springer
Acrylamide is a chemical monomer; its polymer compounds are used in the manufacture of
plastic, papers, adhesive tapes, dyes, and food packaging. Lately, scientists found that …

[HTML][HTML] Exploring the possible neuroprotective and antioxidant potency of lycopene against acrylamide-induced neurotoxicity in rats' brain

SM Farouk, FA Gad, R Almeer, MM Abdel-Daim… - Biomedicine & …, 2021 - Elsevier
Acrylamide (Ac) is a carbonyl compound extracted from hydrated acrylonitrile with a
significantly high chemical activity. It is widely existed and used in food processing, industrial …