Extracellular vesicles and exosomes: insights from exercise science
JP Nederveen, G Warnier, A Di Carlo… - Frontiers in …, 2021 - frontiersin.org
The benefits of exercise on health and longevity are well-established, and evidence
suggests that these effects are partially driven by a spectrum of bioactive molecules …
suggests that these effects are partially driven by a spectrum of bioactive molecules …
Physical exercise as an epigenetic modulator of brain plasticity and cognition
A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …
function, the effects of which can last for considerable time. An emerging line of scientific …
The potential of endurance exercise-derived exosomes to treat metabolic diseases
Endurance exercise-mediated multisystemic adaptations are known to mitigate metabolism-
related disorders such as obesity and type 2 diabetes mellitus (T2DM). However, the …
related disorders such as obesity and type 2 diabetes mellitus (T2DM). However, the …
Skeletal muscle as an endocrine organ: the role of myokines in exercise adaptations
C Hoffmann, C Weigert - Cold Spring …, 2017 - perspectivesinmedicine.cshlp.org
Exercise stimulates the release of proteins with autocrine, paracrine, or endocrine functions
produced in skeletal muscle, termed myokines. Based on the current state of knowledge, the …
produced in skeletal muscle, termed myokines. Based on the current state of knowledge, the …
Circulating microRNAs as biomarkers for sepsis
F Benz, S Roy, C Trautwein, C Roderburg… - International journal of …, 2016 - mdpi.com
Sepsis represents a major cause of lethality during intensive care unit (ICU) treatment.
Pharmacological treatment strategies for sepsis are still limited and mainly based on the …
Pharmacological treatment strategies for sepsis are still limited and mainly based on the …
Physical exercise and epigenetic modifications in skeletal muscle
Physical activity and sports play major roles in the overall health status of humans. It is well
known that regular exercise helps to lower the risk for a broad variety of health problems …
known that regular exercise helps to lower the risk for a broad variety of health problems …
Using ncRNAs as tools in Cancer diagnosis and treatment—the way towards personalized medicine to improve patients' health
Although the first discovery of a non-coding RNA (ncRNA) dates back to 1958, only in recent
years has the complexity of the transcriptome started to be elucidated. However, its …
years has the complexity of the transcriptome started to be elucidated. However, its …
Exosomes as mediators of the systemic adaptations to endurance exercise
A Safdar, MA Tarnopolsky - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Habitual endurance exercise training is associated with multisystemic metabolic adaptations
that lower the risk of inactivity-associated disorders such as obesity and type 2 diabetes …
that lower the risk of inactivity-associated disorders such as obesity and type 2 diabetes …
Muscle releases alpha-sarcoglycan positive extracellular vesicles carrying miRNAs in the bloodstream
In the past few years, skeletal muscle has emerged as an important secretory organ
producing soluble factors, called myokines, that exert either autocrine, paracrine or …
producing soluble factors, called myokines, that exert either autocrine, paracrine or …
[HTML][HTML] Circulating microRNAs as novel biomarkers for bone diseases–complex signatures for multifactorial diseases?
M Hackl, U Heilmeier, S Weilner, J Grillari - Molecular and cellular …, 2016 - Elsevier
Biomarkers are essential tools in clinical research and practice. Useful biomarkers must
combine good measurability, validated association with biological processes or outcomes …
combine good measurability, validated association with biological processes or outcomes …