Cell-penetrating peptides transport therapeutics into cells

JD Ramsey, NH Flynn - Pharmacology & therapeutics, 2015 - Elsevier
Nearly 30 years ago, certain small, relatively nontoxic peptides were discovered to be
capable of traversing the cell membrane. These cell-penetrating peptides, as they are now …

Drug delivery by red blood cells: vascular carriers designed by mother nature

VR Muzykantov - Expert opinion on drug delivery, 2010 - Taylor & Francis
Importance of the field: Vascular delivery of several classes of therapeutic agents may
benefit from carriage by red blood cells (RBC), for example, drugs that require delivery into …

Red blood cells: a potential delivery system

M Chen, Y Leng, C He, X Li, L Zhao, Y Qu… - Journal of …, 2023 - Springer
Red blood cells (RBCs) are the most abundant cells in the body, possessing unique
biological and physical properties. RBCs have demonstrated outstanding potential as …

Erythrocyte‐inspired delivery systems

CMJ Hu, RH Fang, L Zhang - Advanced healthcare materials, 2012 - Wiley Online Library
Herein recent progress in develo** red blood cell (RBC)‐inspired delivery systems is
reviewed, with an emphasis on how our growing understanding of fundamental biological …

Non-genetic engineering of cells for drug delivery and cell-based therapy

Q Wang, H Cheng, H Peng, H Zhou, PY Li… - Advanced drug delivery …, 2015 - Elsevier
Cell-based therapy is a promising modality to address many unmet medical needs. In
addition to genetic engineering, material-based, biochemical, and physical science-based …

Bioengineered cellular and cell membrane-derived vehicles for actively targeted drug delivery: so near and yet so far

MY Thanuja, C Anupama, SH Ranganath - Advanced Drug Delivery …, 2018 - Elsevier
Cellular carriers for drug delivery are attractive alternatives to synthetic nanoparticles owing
to their innate homing/targeting abilities. Here, we review molecular interactions involved in …

[HTML][HTML] Erythrocytes as carriers: From drug delivery to biosensors

L Koleva, E Bovt, F Ataullakhanov, E Sinauridze - Pharmaceutics, 2020 - mdpi.com
Drug delivery using natural biological carriers, especially erythrocytes, is a rapidly
develo** field. Such erythrocytes can act as carriers that prolong the drug's action due to …

[HTML][HTML] Vascular drug delivery using carrier red blood cells: focus on RBC surface loading and pharmacokinetics

PM Glassman, CH Villa, A Ukidve, Z Zhao, P Smith… - Pharmaceutics, 2020 - mdpi.com
Red blood cells (RBC) have great potential as drug delivery systems, capable of producing
unprecedented changes in pharmacokinetics, pharmacodynamics, and immunogenicity …

Therapeutic l-asparaginase: upstream, downstream and beyond

AM Lopes, L Oliveira-Nascimento… - Critical reviews in …, 2017 - Taylor & Francis
Abstract l-asparaginase (l-asparagine amino hydrolase, EC 3.5. 1.1) is an enzyme clinically
accepted as an antitumor agent to treat acute lymphoblastic leukemia and lymphosarcoma …

Design strategies and applications of circulating cell-mediated drug delivery systems

Y Su, Z **e, GB Kim, C Dong… - ACS biomaterials science …, 2015 - ACS Publications
Drug delivery systems, particularly nanomaterial-based drug delivery systems, possess a
tremendous amount of potential to improve the diagnostic and therapeutic effects of drugs …