The impact of population ageing on the burden of chronic kidney disease

NC Chesnaye, A Ortiz, C Zoccali, VS Stel… - Nature Reviews …, 2024 - nature.com
The burden of chronic kidney disease (CKD) and its risk factors are projected to rise in
parallel with the rapidly ageing global population. By 2050, the prevalence of CKD category …

[HTML][HTML] Kynurenine Pathway after Kidney Transplantation: Friend or Foe?

I Zakrocka, EM Urbańska, W Załuska… - International Journal of …, 2024 - mdpi.com
Kidney transplantation significantly improves the survival of patients with end-stage kidney
disease (ESKD) compared to other forms of kidney replacement therapy. However, kidney …

A comparison of the epidemiology of kidney replacement therapy between Europe and the United States: 2021 data of the ERA Registry and the USRDS

VS Stel, R Boenink, ME Astley… - Nephrology Dialysis …, 2024 - academic.oup.com
Background This paper compares the most recent data on the incidence and prevalence of
kidney replacement therapy (KRT), kidney transplantation rates, and mortality on KRT from …

Decreased life expectancy: a health outcome not corrected by kidney replacement therapy that emphasizes the need for primary prevention of CKD

L Cordero, A Ortiz - Clinical Kidney Journal, 2024 - academic.oup.com
The European Renal Association (ERA) Registry Annual Report 2021 was published online
in 2023 [1]. Its data provide a compelling illustration of the need to prevent chronic kidney …

[HTML][HTML] Sorbent-based dialysate regeneration for the wearable artificial kidney: Advancing material innovation via experimental and computational studies

T Fabiani, M Zarghamidehaghani, C Boi… - Separation and …, 2025 - Elsevier
Hemodialysis is the primary renal replacement therapy for patients affected by end-stage
renal disease, but it has a severe impact on the patient's lifestyle and wellbeing, and is …

JiangyaTongluo decoction ameliorates tubulointerstitial fibrosis via regulating the SIRT1/PGC-1α/mitophagy axis in hypertensive nephropathy

Y Zhao, Q Jia, G Hao, L Han, Y Gao, X Zhang… - Frontiers in …, 2024 - frontiersin.org
Introduction With the increasing prevalence of hypertension, the incidence of kidney
diseases is also increasing, resulting in a serious public burden. Jiangya Tongluo decoction …

Actioning the findings of hard endpoint clinical trials as they emerge in the realm of chronic kidney disease care: a review and a call to action

GFM Strippoli, SC Green - Clinical kidney journal, 2024 - academic.oup.com
Fewer than half of patients treated with hemodialysis survive 5 years. Multiple therapeutics
are used to address the complications of advanced chronic kidney disease but most have …

How dialysis frequency and duration impact uremic toxin and fluid removal: a pediatric perspective

P Van Wesemael, S Eloot, A Raes, R Shroff… - Pediatric …, 2024 - Springer
Abstract Three-weekly 4-h hemodialysis/hemodiafiltration (HD/HDF) per week has become
the “standard HD/HDF” regimen in children across the globe, although increasingly …

Aging and chronic kidney disease: epidemiology, therapy, management and the role of immunity

Y Tang, J Jiang, Y Zhao, D Du - Clinical Kidney Journal, 2024 - academic.oup.com
Chronic kidney disease (CKD) is now an unquestionable progressive condition that affects
more than 10% of the general population worldwide, and has emerged as one of the most …

Assisted peritoneal dialysis in Europe: a strategy to increase and maintain home dialysis

M Reyskens, AC Abrahams, K François… - Clinical Kidney …, 2024 - academic.oup.com
Peritoneal dialysis (PD) is a form of kidney replacement therapy with the major advantage
that it can be performed at home. This has a positive impact on patients' autonomy and …