[HTML][HTML] Drug-induced oxidative stress in cancer treatments: Angel or devil?

H Jiang, J Zuo, B Li, R Chen, K Luo, X **, K Liu… - European Journal of …, 2022 - Elsevier
Background Chemotherapy-related cognitive impairment (CRCI) is highly prevalent in
patients with cancer and is associated with poor outcomes and quality of life. To date, the …

Reduced hippocampal volume and verbal memory performance associated with interleukin-6 and tumor necrosis factor-alpha levels in chemotherapy-treated breast …

S Kesler, M Janelsins, D Koovakkattu, O Palesh… - Brain, behavior, and …, 2013 - Elsevier
Many survivors of breast cancer show significant cognitive impairments, including memory
deficits. Inflammation induced by chemotherapy may contribute to hippocampal changes …

Impaired cognitive function and hippocampal neurogenesis following cancer chemotherapy

LA Christie, MM Acharya, VK Parihar, A Nguyen… - Clinical cancer …, 2012 - AACR
Purpose: A substantial proportion of breast cancer survivors report significant, long-lasting
impairments in cognitive function, often referred to as “chemobrain.” Advances in detection …

Redox proteomics: chemical principles, methodological approaches and biological/biomedical promises

A Bachi, I Dalle-Donne, A Scaloni - Chemical reviews, 2013 - ACS Publications
Inevitable byproducts of aerobic metabolism are free radicals and other highly reactive
oxidants and nitrosants that are continuously formed within cells. Most cells generally …

Doxorubicin-induced elevated oxidative stress and neurochemical alterations in brain and cognitive decline: protection by MESNA and insights into mechanisms of …

JTR Keeney, X Ren, G Warrier, T Noel, DK Powell… - …, 2018 - pmc.ncbi.nlm.nih.gov
Chemotherapy-induced cognitive impairment (CICI) is now widely recognized as a real and
too common complication of cancer chemotherapy experienced by an ever-growing number …

Nose-to-brain delivery of chrysin transfersomal and composite vesicles in doxorubicin-induced cognitive impairment in rats: Insights on formulation, oxidative stress …

SS Ibrahim, OGA Elseoud, MH Mohamedy, MM Amer… - …, 2021 - Elsevier
Many cancer survivors suffer from chemotherapy-induced cognitive impairment known as
'Chemobrain'. Doxorubicin-topoisomerase II inhibitor-is widely used in breast cancer …

Chemobrain: a critical review and causal hypothesis of link between cytokines and epigenetic reprogramming associated with chemotherapy

XM Wang, B Walitt, L Saligan, AFY Tiwari, CW Cheung… - Cytokine, 2015 - Elsevier
One consequence of modern cancer therapy is chemotherapy related cognitive dysfunction
or “chemobrain”, the subjective experience of cognitive deficits at any point during or …