Verifiable biology

S Konur, M Gheorghe… - Journal of the Royal …, 2023 - royalsocietypublishing.org
The formalization of biological systems using computational modelling approaches as an
alternative to mathematical-based methods has recently received much interest because …

Spiking neural P systems: matrix representation and formal verification

M Gheorghe, R Lefticaru, S Konur, IM Niculescu… - Journal of Membrane …, 2021 - Springer
Structural and behavioural properties of models are very important in development of
complex systems and applications. In this paper, we investigate such properties for some …

Technologies for design-build-test-learn automation and computational modelling across the synthetic biology workflow: a review

R Matzko, S Konur - Network Modeling Analysis in Health Informatics and …, 2024 - Springer
Motivated by the need to parameterize and functionalize dynamic, multiscale simulations, as
well as bridge the gap between advancing in silico and laboratory Synthetic Biology …

[HTML][HTML] kPWorkbench: A software suit for membrane systems

S Konur, L Mierlă, F Ipate, M Gheorghe - SoftwareX, 2020 - Elsevier
Membrane computing is a new natural computing paradigm inspired by the functioning and
structure of biological cells, and has been successfully applied to many different areas, from …

An integrated model checking toolset for kernel P systems

M Gheorghe, S Konur, F Ipate, L Mierla… - … Conference, CMC 2015 …, 2015 - Springer
P systems are the computational models introduced in the context of membrane computing,
a computational paradigm within the more general area of unconventional computing …

Kernel P systems and stochastic P systems for modelling and formal verification of genetic logic gates

M Gheorghe, S Konur, F Ipate - Advances in Unconventional Computing …, 2017 - Springer
P systems are the computational models of membrane computing, a computing paradigm
within natural computing area inspired by the structure and behaviour of the living cell. In …

Extended simulation and verification platform for kernel P systems

ME Bakir, F Ipate, S Konur, L Mierla… - … Conference, CMC 2014 …, 2014 - Springer
Kernel P systems integrate in a coherent and elegant manner many of the features of
different P system variants, successfully used for modelling various applications. In this …

Qualitative and quantitative analysis of systems and synthetic biology constructs using P systems

S Konur, M Gheorghe, C Dragomir, L Mierla… - ACS Synthetic …, 2015 - ACS Publications
Computational models are perceived as an attractive alternative to mathematical models
(eg, ordinary differential equations). These models incorporate a set of methods for …

A property-driven methodology for formal analysis of synthetic biology systems

S Konur, M Gheorghe - IEEE/ACM Transactions on …, 2014 - ieeexplore.ieee.org
This paper proposes a formal methodology to analyse bio-systems, in particular synthetic
biology systems. An integrative analysis perspective combining different model checking …

High performance simulations of kernel P systems

ME Bakir, S Konur, M Gheorghe… - 2014 IEEE Intl Conf …, 2014 - ieeexplore.ieee.org
The paper presents the use of a membrane computing model for specifying a synthetic
biology pulse generator example and discusses some simulation results produced by the …