RAGE and its ligands: molecular interplay between glycation, inflammation, and hallmarks of cancer—a review
G Palanissami, SFD Paul - Hormones and Cancer, 2018 - Springer
Risk of cancer especially of colon, breast, and pancreas is high in diabetic and obese
patients, with potential involvement of augmented expression of RAGE (receptor for …
patients, with potential involvement of augmented expression of RAGE (receptor for …
AGE-RAGE synergy influences programmed cell death signaling to promote cancer
Advanced glycation end products (AGEs) are formed as a result of non-enzymatic reaction
between the free reducing sugars and proteins, lipids, or nucleic acids. AGEs are …
between the free reducing sugars and proteins, lipids, or nucleic acids. AGEs are …
Molecular characteristics of RAGE and advances in small-molecule inhibitors
HJ Kim, MS Jeong, SB Jang - International journal of molecular sciences, 2021 - mdpi.com
Receptor for advanced glycation end-products (RAGE) is a member of the immunoglobulin
superfamily. RAGE binds and mediates cellular responses to a range of DAMPs (damage …
superfamily. RAGE binds and mediates cellular responses to a range of DAMPs (damage …
Insulin/IGF axis and the Receptor for Advanced Glycation End Products: role in meta-inflammation and potential in cancer therapy
In metabolic conditions such as obesity and diabetes, which are associated with
deregulated signaling of the insulin/insulin-like growth factor system (IIGFs), inflammation …
deregulated signaling of the insulin/insulin-like growth factor system (IIGFs), inflammation …
RAGE and its ligands: from pathogenesis to therapeutics
Receptor for advanced glycation end products (RAGE) is an immunoglobulin-like receptor
present on cell surface. RAGE binds to an array of structurally diverse ligands, acts as a …
present on cell surface. RAGE binds to an array of structurally diverse ligands, acts as a …
Role and mechanisms of RAGE-ligand complexes and RAGE-inhibitors in cancer progression
Interactions of the receptor for advanced glycation end product (RAGE) and its ligands in the
context of their role in diabetes mellitus, inflammation, and carcinogenesis have been …
context of their role in diabetes mellitus, inflammation, and carcinogenesis have been …
[HTML][HTML] Food advanced glycation end products as potential endocrine disruptors: An emerging threat to contemporary and future generation
Mankind exposure to chemicals in the past century has increased dramatically throughout
environment. There is no question that chemicals interfere with the physiology of biological …
environment. There is no question that chemicals interfere with the physiology of biological …
Diabetes and pancreatic cancer—A dangerous liaison relying on carbonyl stress
Simple Summary Diabetic people have an increased risk of develo** several types of
cancers, particularly pancreatic cancer. The higher availability of glucose and/or lipids that …
cancers, particularly pancreatic cancer. The higher availability of glucose and/or lipids that …
The dual-role of methylglyoxal in tumor progression–novel therapeutic approaches
A Leone, C Nigro, A Nicolò, I Prevenzano… - Frontiers in …, 2021 - frontiersin.org
One of the hallmarks of cancer cells is their metabolic reprogramming, which includes the
preference for the use of anaerobic glycolysis to produce energy, even in presence of …
preference for the use of anaerobic glycolysis to produce energy, even in presence of …
Dietary advanced glycation end products and the risk of postmenopausal breast cancer in the National Institutes of Health‐AARP diet and health study
Background Advanced glycation end products (AGEs) are reactive metabolites produced as
a by‐product of sugar metabolism and are consumed through the diet in high‐fat and highly …
a by‐product of sugar metabolism and are consumed through the diet in high‐fat and highly …