Sex determination, gonadal sex differentiation, and plasticity in vertebrate species

Y Nagahama, T Chakraborty… - Physiological …, 2021 - journals.physiology.org
A diverse array of sex determination (SD) mechanisms, encompassing environmental to
genetic, have been found to exist among vertebrates, covering a spectrum from fixed SD …

Sex determination mechanisms and sex control approaches in aquaculture animals

XY Li, J Mei, CT Ge, XL Liu, JF Gui - Science China Life Sciences, 2022 - Springer
Aquaculture is one of the most efficient modes of animal protein production and plays an
important role in global food security. Aquaculture animals exhibit extraordinarily diverse …

Aging is associated with a systemic length-associated transcriptome imbalance

T Stoeger, RA Grant, AC McQuattie-Pimentel… - Nature Aging, 2022 - nature.com
Aging is among the most important risk factors for morbidity and mortality. To contribute
toward a molecular understanding of aging, we analyzed age-resolved transcriptomic data …

Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates

W Wang, CK Hu, A Zeng, D Alegre, D Hu, K Gotting… - Science, 2020 - science.org
INTRODUCTION The ability to regenerate tissues lost to damage or disease is widely but
nonuniformly distributed in vertebrates. Some animals such as teleost fishes can regenerate …

Vertebrate sex determination: evolutionary plasticity of a fundamental switch

B Capel - Nature Reviews Genetics, 2017 - nature.com
The discovery of the Sry gene in 1990 triggered a revolution in our understanding of sex
determination. More recently, advances in non-model organisms have been fuelled by the …

Regulation of life span by the gut microbiota in the short-lived African turquoise killifish

P Smith, D Willemsen, M Popkes, F Metge, E Gandiwa… - elife, 2017 - elifesciences.org
Gut bacteria occupy the interface between the organism and the external environment,
contributing to homeostasis and disease. Yet, the causal role of the gut microbiota during …

Sex chromosome evolution: so many exceptions to the rules

BLS Furman, DCH Metzger, I Darolti… - Genome biology and …, 2020 - academic.oup.com
Genomic analysis of many nonmodel species has uncovered an incredible diversity of sex
chromosome systems, making it possible to empirically test the rich body of evolutionary …

The genetics of aging: a vertebrate perspective

PP Singh, BA Demmitt, RD Nath, A Brunet - Cell, 2019 - cell.com
Aging negatively impacts vitality and health. Many genetic pathways that regulate aging
were discovered in invertebrates. However, the genetics of aging is more complex in …

Evolution of master sex determiners: TGF-β signalling pathways at regulatory crossroads

Q Pan, T Kay, A Depincé, M Adolfi… - … of the Royal …, 2021 - royalsocietypublishing.org
To date, more than 20 different vertebrate master sex-determining genes have been
identified on different sex chromosomes of mammals, birds, frogs and fish. Interestingly, six …

Non-model model organisms

JJ Russell, JA Theriot, P Sood, WF Marshall… - BMC biology, 2017 - Springer
Abstract Model organisms are widely used in research as accessible and convenient
systems to study a particular area or question in biology. Traditionally only a handful of …