[HTML][HTML] Biofilms as battlefield armor for bacteria against antibiotics: Challenges and combating strategies

S Bano, N Hassan, M Rafiq, F Hassan, M Rehman… - Microorganisms, 2023 - mdpi.com
Bacterial biofilms are formed by communities, which are encased in a matrix of extracellular
polymeric substances (EPS). Notably, bacteria in biofilms display a set of 'emergent …

Ion traps in modern mass spectrometry

D Nolting, R Malek, A Makarov - Mass spectrometry reviews, 2019 - Wiley Online Library
This review is devoted to trap** mass spectrometry wherein ions are confined by
electromagnetic fields for prolonged periods of time within limited volume, with mass …

Dual antibacterial activities of a chitosan-modified upconversion photodynamic therapy system against drug-resistant bacteria in deep tissue

S Li, S Cui, D Yin, Q Zhu, Y Ma, Z Qian, Y Gu - Nanoscale, 2017 - pubs.rsc.org
Photodynamic therapy (PDT) has recently been proposed as an innovative approach to
combat multi-drug resistant (MDR) bacteria. To improve the penetration depth of current …

Adaptive laboratory evolution and independent component analysis disentangle complex vancomycin adaptation trajectories

A Fait, Y Seif, K Mikkelsen, S Poudel, JM Wells… - Proceedings of the …, 2022 - pnas.org
Human infections with methicillin-resistant Staphylococcus aureus (MRSA) are commonly
treated with vancomycin, and strains with decreased susceptibility, designated as …

Development of antiseptic adaptation and cross-adapatation in selected oral pathogens in vitro

T Verspecht, E Rodriguez Herrero, L Khodaparast… - Scientific reports, 2019 - nature.com
There is evidence that pathogenic bacteria can adapt to antiseptics upon repeated
exposure. More alarming is the concomitant increase in antibiotic resistance that has been …

Impact of antibiotics with various target sites on the metabolome of Staphylococcus aureus

K Dörries, R Schlueter, M Lalk - Antimicrobial agents and …, 2014 - journals.asm.org
In this study, global intra-and extracellular metabolic profiles were exploited to investigate
the impact of antibiotic compounds with different cellular targets on the metabolome of …

Deletion of membrane‐associated Asp23 leads to upregulation of cell wall stress genes in Staphylococcus aureus

M Müller, S Reiß, R Schlüter, U Mäder… - Molecular …, 2014 - Wiley Online Library
With about 25 000 molecules per cell, Asp 23 is one of the most abundant proteins in St
aphylococcus aureus. Asp 23 has been characterized as a protein that, following an alkaline …

The general stress response of Staphylococcus aureus promotes tolerance of antibiotics and survival in whole human blood

N Ranganathan, R Johnson, AM Edwards - Microbiology, 2020 - microbiologyresearch.org
Staphylococcus aureus is a frequent cause of invasive human infections such as
bacteraemia and infective endocarditis. These infections frequently relapse or become …

[PDF][PDF] Proteomics in studies of Staphylococcus aureus virulence.

E Bonar, I Wójcik, B Wladyka - Acta Biochimica Polonica, 2015 - frontierspartnerships.org
Staphylococcus aureus is a widespread, opportunistic pathogen that causes community and
hospital acquired infections. Its high pathogenicity is driven by multifactorial and complex …

Differential daptomycin resistance development in Staphylococcus aureus strains with active and mutated gra regulatory systems

A Müller, F Grein, A Otto, K Gries, D Orlov… - International Journal of …, 2018 - Elsevier
The first-in-class lipopeptide antibiotic daptomycin (DAP) is highly active against Gram-
positive pathogens including ß-lactam and glycopeptide resistant strains. Its molecular mode …