Mycobacterium tuberculosis (Mtb) can withstand months of antibiotic treatment. An important
goal of tuberculosis research is to shorten the treatment to reduce the burden on patients …

ABSTRACT Introduction: The treatment of Mycobacterium abscessus lung disease faces
significant challenges due to intrinsic antibiotic resistance. New drugs are needed to cure …

Intracellular replication of the deadly pathogen Mycobacterium tuberculosis relies on the
production of small organic molecules called siderophores that scavenge iron from host …

Mycobacterium tuberculosis is protected from antibiotic therapy by a multi-layered
hydrophobic cell envelope. Major facilitator superfamily (MFS) transporter Rv1410 and the …

Purpose The emergence of clarithromycin resistance is a challenge in treating
Mycobacterium abscessus infections. Known mechanisms that contribute to intrinsic …

Membrane proteins play key roles in most crucial cellular processes, ranging from cell-to-
cell communication to signaling processes. Despite recent improvements, the expression of …

Background Taurine, a semi-essential micronutrient, could be utilized as a sulfur source for
some bacteria; however, little is known about its effect on the accumulation of fermentation …

Almost 3% of the proteins of Mycobacterium tuberculosis (M. tuberculosis), the main
causative agent of human tuberculosis, are lipoproteins. These lipoproteins are …

Invading microbes face a myriad of cidal mechanisms of phagocytes that inflict physical
damage to microbial structures. How intracellular bacterial pathogens adapt to these …

Mycobacterium tuberoculosis (Mtb) is a contagious pathogen that causes human
tuberculosis (TB). TB is a major global health threat that causes 9.6 million illnesses and 1.5 …