Epithelial ovarian cancer (EOC) is a gynecologic malignancy with a poor prognosis due to
resistance to first-line chemotherapeutic agents. Some cancer cells are primarily dependent …

Cancer cells adapt to environmental changes and alter their metabolic pathways to promote
survival and proliferation. Metabolic reprogramming not only allows tumor cells to maintain a …

Drug delivery vehicles have made a great impact on cancer immunotherapies in clinics and
pre-clinical research. Notably, the science of delivery of cancer vaccines and …

The mortality rate of epithelial ovarian cancer (EOC) remains the first in malignant tumors of
the female reproductive system. The characteristics of rapid proliferation, extensive …

Glycolysis is the preferred energy metabolism pathway in cancer cells even when the
oxygen content is sufficient. Through glycolysis, cancer cells convert glucose into pyruvic …

Background Most ovarian cancers are diagnosed at advanced stages characterized by
abdominal dissemination and frequently exhibit chemoresistance. Pyruvate dehydrogenase …

Epithelial ovarian cancer (EOC) is associated with a dismal prognosis due to development
of resistance to chemotherapy and metastasis in the peritoneal cavity and distant organs. In …

Ovarian cancer (OC) represents one of the most detrimental gynecological malignancies.
RNA‐binding protein eukaryotic translation initiation factor 4A isoform 3 (EIF4A3) is well …

From the seminal observation of Otto Warburg regarding the cancer-specific energetic
requirement to enhance glycolysis over oxidative phosphorylation (OXPHOS), also under …

Digital pathology has the potential to quantify tumor markers accurately and reproducibly
with various cellular and subcellular localizations in tissues, thus filling a need in cancer …