Genome rearrangement problems arise in both species evolution and cancer research.
Basic genome rearrangement models assume that the genome contains a single copy of …

Recently we developed a gene orthology inference tool based on genome rearrangements
(Journal of Bioinformatics and Computational Biology 19: 6, 2021). Given a set of genomes …

Background A classical problem in comparative genomics is to compute the rearrangement
distance, that is the minimum number of large-scale rearrangements required to transform a …

Background Recently we developed a gene orthology inference tool based on genome
rearrangements (Journal of Bioinformatics and Computational Biology 19: 6, 2021). Given a …

Recently, we proposed an efficient ILP formulation [Rubert DP, Martinez FV, Braga MDV,
Natural family-free genomic distance, Algorithms Mol Biol 16: 4, 2021] for exactly computing …

Motivation The phylogenetic signal of structural variation informs a more comprehensive
understanding of evolution. As (near-) complete genome assembly becomes more …

Whole Genome Duplications (WGDs) are events that double the content and structure of a
genome. In some organisms, multiple WGD events have been observed while loss of …

Phylogenetic inference based on genomic structural variations, that manipulate the gene
order and content of whole chromosomes, promises to inform a more comprehensive …

Supplementary Figure S1-1: Runs and indel-potential of a path in the relational diagram.(i) A
BB-path with 4 runs.(ii) After an optimal DCJ that creates a new cycle, one A-run is …